Is Cronkhite-Canada Syndrome necessarily a late-onset disease?

Piero Vernia, Adriana Marcheggiano, Vanessa Marinaro, Santo Morabito, Isabella Guzzo, Alessandro Pierucci

Research output: Contribution to journalArticle

Abstract

Cronkhite-Canada Syndrome is a non-inherited, non-congenital disease characterized by juvenile hamartomatous gastrointestinal polyps with a typically late onset. In the case described herein the disease was diagnosed in a 17-year-old male with type I diabetes and thalassaemia minor, in coincidence with severe symptomatic intestinal candidiasis. Following the disappearance of the mycosis and correction of the protein and electrolyte imbalance, the ectodermal abnormalities returned to normal and the patient remained asymptomatic during a 7-year follow-up period, despite proteinuria resulting from membranous glomerulopathy. The concept that Cronkhite-Canada Syndrome is a late-onset disease should probably be reconsidered as it may remain asymptomatic, and thus not diagnosed, for a long a time.

Original languageEnglish
Pages (from-to)1139-1141
Number of pages3
JournalEuropean Journal of Gastroenterology and Hepatology
Volume17
Issue number10
DOIs
Publication statusPublished - Oct 2005

Fingerprint

Intestinal Polyposis
Membranous Glomerulonephritis
Mycoses
Candidiasis
beta-Thalassemia
Polyps
Type 1 Diabetes Mellitus
Proteinuria
Electrolytes
Proteins
Late Onset Disorders

Keywords

  • Cronkhite-Canada Syndrome
  • Juvenile polyposis
  • Polyposis

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Is Cronkhite-Canada Syndrome necessarily a late-onset disease? / Vernia, Piero; Marcheggiano, Adriana; Marinaro, Vanessa; Morabito, Santo; Guzzo, Isabella; Pierucci, Alessandro.

In: European Journal of Gastroenterology and Hepatology, Vol. 17, No. 10, 10.2005, p. 1139-1141.

Research output: Contribution to journalArticle

Vernia, Piero ; Marcheggiano, Adriana ; Marinaro, Vanessa ; Morabito, Santo ; Guzzo, Isabella ; Pierucci, Alessandro. / Is Cronkhite-Canada Syndrome necessarily a late-onset disease?. In: European Journal of Gastroenterology and Hepatology. 2005 ; Vol. 17, No. 10. pp. 1139-1141.
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