TY - JOUR
T1 - Is frontotemporal lobar degeneration a rare disorder? Evidence from a preliminary study in Brescia County, Italy
AU - Borroni, Barbara
AU - Alberici, Antonella
AU - Grassi, Mario
AU - Turla, Marinella
AU - Zanetti, Orazio
AU - Bianchetti, Angelo
AU - Volta, Giorgio Dalla
AU - Rozzini, Renzo
AU - Gilberti, Nicola
AU - Bellelli, Giuseppe
AU - Padovani, Alessandro
PY - 2010
Y1 - 2010
N2 - Frontotemporal Lobar Degeneration (FTLD) has always been considered a rare disorder, but only a few epidemiologic studies are available. The aim of the present work was to ascertain all FTLD patients in a Northern Italy area from January 2001 to December 2008, and to estimate the disease prevalence. On the census day, 213 FTD patients were still alive, resulting in an overall prevalence of 17.6 per 100,000 inhabitants. The prevalence of FTLD in patients aged 45-65 years was 22 per 100,000 inhabitants (95% CI=17-27). The prevalence of FTLD was the highest in patients aged 66-75 (78 per 100,000 inhabitants, 95% CI=56-100), and it was still high over 75 years (54 per 100,000 inhabitants, 95% CI=36-69). FTLD is a more common form of dementia than previously recognized. Our results claimed that FTLD is not only an early-onset disorder, but it is frequent in advanced age as well.
AB - Frontotemporal Lobar Degeneration (FTLD) has always been considered a rare disorder, but only a few epidemiologic studies are available. The aim of the present work was to ascertain all FTLD patients in a Northern Italy area from January 2001 to December 2008, and to estimate the disease prevalence. On the census day, 213 FTD patients were still alive, resulting in an overall prevalence of 17.6 per 100,000 inhabitants. The prevalence of FTLD in patients aged 45-65 years was 22 per 100,000 inhabitants (95% CI=17-27). The prevalence of FTLD was the highest in patients aged 66-75 (78 per 100,000 inhabitants, 95% CI=56-100), and it was still high over 75 years (54 per 100,000 inhabitants, 95% CI=36-69). FTLD is a more common form of dementia than previously recognized. Our results claimed that FTLD is not only an early-onset disorder, but it is frequent in advanced age as well.
KW - Epidemiology
KW - Frontotemporal Dementia
KW - Frontotemporal Lobar Degeneration
KW - Prevalence
KW - Rare disease
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U2 - 10.3233/JAD-2010-1208
DO - 10.3233/JAD-2010-1208
M3 - Article
C2 - 20061630
AN - SCOPUS:75149132914
VL - 19
SP - 111
EP - 116
JO - Journal of Alzheimer's Disease
JF - Journal of Alzheimer's Disease
SN - 1387-2877
IS - 1
ER -