È utile l'urokinasi intrapleurica nel trattamento dell'empiema? Una risposta da una esperienza concreta

Translated title of the contribution: Is intrapleural urokinase effective in the treatment of empyema?

Letizia Bogdanovits, Egidio Barbi, Federico Marchetti, Nagua Giurici, Luca Ronfani, Alessandro Ventura

Research output: Contribution to journalArticle

Abstract

The use of intrapleural fibrynolisis in the treatment of empyema shortens hospital stay and is recommended by international guidelines in children with a B grade of evidence. Even though only few randomized studies have addressed this issue in limited series of patients with conflicting results. One trial for urokinase showed a positive result while another trial with streptokinase did not show a significant reduction in length of hospital stay. We retrospectively rewied a 30 year experience in a third level university hospital comparing length of treatment in a group of children treated with simple drainage and a group treated with urokinase. Even if such a retrospective analysis is limited by possible biases which are highlighted and discussed a significant reduction in length of hospital stay was found without side effects.

Translated title of the contributionIs intrapleural urokinase effective in the treatment of empyema?
Original languageItalian
Pages (from-to)97-102
Number of pages6
JournalMedico e Bambino
Volume26
Issue number2
Publication statusPublished - Feb 28 2007

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Fingerprint Dive into the research topics of 'Is intrapleural urokinase effective in the treatment of empyema?'. Together they form a unique fingerprint.

  • Cite this