Is one motor cortex enough for two hands?

Simona Fiori, Martin Staudt, Kerstin Pannek, Davide Borghetti, Laura Biagi, Danilo Scelfo, Stephen E. Rose, Michela Tosetti, Giovanni Cioni, Andrea Guzzetta

Research output: Contribution to journalArticlepeer-review

Abstract

We report on a patient with mirror movements sustained by a mono-hemispheric fast control of bilateral hand muscles and normal hand function. Transcranial magnetic stimulation of the right motor cortex evoked contractions of muscles in both hands while no responses were observed from the left hemisphere. Somatosensory-evoked potentials, functional magnetic resonance, and diffusion tractography showed evidence of sensorimotor dissociation and asymmetry of corticospinal projections, suggestive of reorganization after early unilateral left brain lesion. This is the first evidence that, in certain rare conditions, good hand function is possible with ipsilateral corticospinal reorganization, supporting the role of unexplored mechanisms of motor recovery. What this paper adds: Good motor control is possible with ipsilateral corticospinal reorganization. This article is commented on by Basu on pages 897-898 of this issue.

Original languageEnglish
Pages (from-to)977-980
Number of pages4
JournalDevelopmental Medicine and Child Neurology
Volume57
Issue number10
DOIs
Publication statusPublished - Oct 1 2015

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience

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