Is propranolol compounding from tablet safe for pediatric use? Results from an experimental test

A. Casiraghi; U. M. Musazzi; I. Franceschini; I. Berti; V. Paragò; L. Cardosi; P. Minghetti

Is propranolol compounding from tablet safe for pediatric use? Results from an experimental test

A. Casiraghi, U. M. Musazzi, I. Franceschini, I. Berti, V. Paragò, L. Cardosi, P. Minghetti

IRCCS pediatrico Burlo Garofolo

Research output: Contribution to journal › Article › peer-review

Abstract

Aim: Although propranolol is widely used in the treatment of infantile hemangiomas, the standard 40 mg tablet needs to be fractioned to obtain 10 mg parts, with even lower doses (i.e., 2-3 mg/kg/day divided into 2-3 daily doses) required in infants. This study evaluated the weight and dose uniformity in split quarters of propranolol tablets.

Original language	English
Pages (from-to)	355-362
Number of pages	8
Journal	Minerva Pediatrica
Volume	66
Issue number	5
Publication status	Published - Oct 1 2014

Keywords

Capillary
Child
Hemangioma
Propranolol

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Medicine(all)

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AU - Casiraghi, A.

AU - Musazzi, U. M.

AU - Franceschini, I.

AU - Berti, I.

AU - Paragò, V.

AU - Cardosi, L.

AU - Minghetti, P.

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N2 - Aim: Although propranolol is widely used in the treatment of infantile hemangiomas, the standard 40 mg tablet needs to be fractioned to obtain 10 mg parts, with even lower doses (i.e., 2-3 mg/kg/day divided into 2-3 daily doses) required in infants. This study evaluated the weight and dose uniformity in split quarters of propranolol tablets.

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KW - Capillary

KW - Child

KW - Hemangioma

KW - Propranolol

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