Is PSA useful in the diagnosis and monitoring of parotid adenocarcinomas?

Cristiana Bergamini, Marta Barisella, Laura D. Locati, Paolo Bossi, Paolo Potepan, Gaetana Rinaldi, Lisa Licitra

Research output: Chapter in Book/Report/Conference proceedingChapter


We report the case of a patient with Androgen's Receptor (AR) and PSA positive parotid adenocarcinoma, who developed skeletal and bone marrow lesions in presence of elevated seric PSA values (142 μg/L). The tumor cells infiltrating the bone marrow were found positive for both AR and PSA, mimicking clinical and immunohistochemical metastases from prostate cancer, which was definitively ruled out. These observations suggest that in salivary gland metastatic AR-positive carcinomas seric PSA evaluation might be useful for the disease monitoring. Androgen deprivation, previously reported as beneficial in a few cases, should be further investigated.

Original languageEnglish
Title of host publicationOral Oncology Extra
Number of pages3
Publication statusPublished - Oct 2005


  • Adenocarcinoma
  • PSA
  • Salivary glad tumors

ASJC Scopus subject areas

  • Oncology
  • Otorhinolaryngology
  • Pathology and Forensic Medicine
  • Oral Surgery


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