Is PSA useful in the diagnosis and monitoring of parotid adenocarcinomas?

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

We report the case of a patient with Androgen's Receptor (AR) and PSA positive parotid adenocarcinoma, who developed skeletal and bone marrow lesions in presence of elevated seric PSA values (142 μg/L). The tumor cells infiltrating the bone marrow were found positive for both AR and PSA, mimicking clinical and immunohistochemical metastases from prostate cancer, which was definitively ruled out. These observations suggest that in salivary gland metastatic AR-positive carcinomas seric PSA evaluation might be useful for the disease monitoring. Androgen deprivation, previously reported as beneficial in a few cases, should be further investigated.

Original languageEnglish
Title of host publicationOral Oncology Extra
Pages219-221
Number of pages3
Volume41
Edition9
DOIs
Publication statusPublished - Oct 2005

Keywords

  • Adenocarcinoma
  • PSA
  • Salivary glad tumors

ASJC Scopus subject areas

  • Oncology
  • Otorhinolaryngology
  • Pathology and Forensic Medicine
  • Oral Surgery

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