Is retrograde intrarenal surgery a viable treatment option for renal stones in patients with solitary kidney?

G. Giusti, S. Proietti, L. Cindolo, R. Peschechera, G. Sortino, F. Berardinelli, G. Taverna

Research output: Contribution to journalArticlepeer-review


Purpose: To evaluate the effectiveness and safety of retrograde intrarenal surgery (RIRS) for stones up to 2 cm in diameter in patients with solitary kidney.

Methods: From January 2008 to January 2013, we prospectively enrolled all consecutive patients with solitary kidney and renal stones. Plain abdominal computed tomography scan was performed preoperatively and 1 month after the procedure to assess the stone-free rates (SFR). Serum creatinine levels were detected preoperatively, at day 1 postoperatively, at 1 month postoperatively, and then every 6 months postoperatively.

Results: During the study period, we prospectively enrolled a total of 29 patients. The mean age was 55.7 ± 12.3 years; the mean stone size was 1.3 ± 0.4 cm. The primary SFR was 72.4 %; the secondary SFR was 93.1 %. The mean number of procedures per patient was 1.24. The mean serum creatinine levels were 1.5 ± 0.6, 1.6 ± 0.7, 1.6 ± 0.6, and 1.7 ± 0.7 mg/dl preoperatively, at 1 day after RIRS, at 1 month after RIRS, and at 1 year after RIRS, respectively, without detection of any statistical difference (p = 0.76). Median follow-up time was 35.7 ± 19.3 (12–72) months, but that was available for only 18 patients. The mean serum creatinine level at the last follow-up was 1.7 ± 0.9 mg/dl. No major complications were recorded. Grade I complications occurred in eight patients (27.4 %).

Conclusions: RIRS is safe and effective in the treatment of renal stones in patients with solitary kidney, without worsening renal function.

Original languageEnglish
Pages (from-to)309-314
Number of pages6
JournalWorld Journal of Urology
Issue number3
Publication statusPublished - 2015


  • Renal function
  • Retrograde intrarenal surgery
  • Solitary kidney
  • Stone

ASJC Scopus subject areas

  • Urology


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