Is screening for thyroid carcinoma indicated in familial adenomatous polyposis?

C. Bülow, S. Bülow, T. Berk, L. Bertario, J. Church, G. Evans, K. Neale, J. G. Park, M. Rodriguez-Bigas, F. Seow-Choen, H. Vasen, G. Winde

Research output: Contribution to journalArticlepeer-review


Forty-five polyposis patients with thyroid carcinoma constituted 1.2% of the patients in the Leeds Castle Polyposis Group database. The patients were diagnosed during 1959-1995; 44 were females at a median age of 25 years (range 10-40) and 37 (82%) had papillary carcinoma. At the end of 1995 only one patient (9%) had died from thyroid carcinoma, and the ten-year cumulative survival was 84% (95% confidence limits 72-97). Due to the low incidence of thyroid carcinoma in FAP acid the good prognosis we do not recommend a regular thyroid screening in polyposis, as this is unlikely to result in a reduction of the mortality, but will only aggravate existing cancrophobia in these strained patients.

Original languageEnglish
Pages (from-to)240-242
Number of pages3
JournalInternational Journal of Colorectal Disease
Issue number4
Publication statusPublished - Aug 1997

ASJC Scopus subject areas

  • Gastroenterology


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