Is screening for thyroid carcinoma indicated in familial adenomatous polyposis?

C. Bülow, S. Bülow, T. Berk, L. Bertario, J. Church, G. Evans, K. Neale, J. G. Park, M. Rodriguez-Bigas, F. Seow-Choen, H. Vasen, G. Winde

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Abstract

Forty-five polyposis patients with thyroid carcinoma constituted 1.2% of the patients in the Leeds Castle Polyposis Group database. The patients were diagnosed during 1959-1995; 44 were females at a median age of 25 years (range 10-40) and 37 (82%) had papillary carcinoma. At the end of 1995 only one patient (9%) had died from thyroid carcinoma, and the ten-year cumulative survival was 84% (95% confidence limits 72-97). Due to the low incidence of thyroid carcinoma in FAP acid the good prognosis we do not recommend a regular thyroid screening in polyposis, as this is unlikely to result in a reduction of the mortality, but will only aggravate existing cancrophobia in these strained patients.

Original languageEnglish
Pages (from-to)240-242
Number of pages3
JournalInternational Journal of Colorectal Disease
Volume12
Issue number4
DOIs
Publication statusPublished - Aug 1997

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Adenomatous Polyposis Coli
Thyroid Neoplasms
Papillary Carcinoma
Thyroid Gland
Databases
Acids
Survival
Mortality
Incidence

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Bülow, C., Bülow, S., Berk, T., Bertario, L., Church, J., Evans, G., ... Winde, G. (1997). Is screening for thyroid carcinoma indicated in familial adenomatous polyposis? International Journal of Colorectal Disease, 12(4), 240-242. https://doi.org/10.1007/s003840050097

Is screening for thyroid carcinoma indicated in familial adenomatous polyposis? / Bülow, C.; Bülow, S.; Berk, T.; Bertario, L.; Church, J.; Evans, G.; Neale, K.; Park, J. G.; Rodriguez-Bigas, M.; Seow-Choen, F.; Vasen, H.; Winde, G.

In: International Journal of Colorectal Disease, Vol. 12, No. 4, 08.1997, p. 240-242.

Research output: Contribution to journalArticle

Bülow, C, Bülow, S, Berk, T, Bertario, L, Church, J, Evans, G, Neale, K, Park, JG, Rodriguez-Bigas, M, Seow-Choen, F, Vasen, H & Winde, G 1997, 'Is screening for thyroid carcinoma indicated in familial adenomatous polyposis?', International Journal of Colorectal Disease, vol. 12, no. 4, pp. 240-242. https://doi.org/10.1007/s003840050097
Bülow, C. ; Bülow, S. ; Berk, T. ; Bertario, L. ; Church, J. ; Evans, G. ; Neale, K. ; Park, J. G. ; Rodriguez-Bigas, M. ; Seow-Choen, F. ; Vasen, H. ; Winde, G. / Is screening for thyroid carcinoma indicated in familial adenomatous polyposis?. In: International Journal of Colorectal Disease. 1997 ; Vol. 12, No. 4. pp. 240-242.
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