Is surgery for non-small cell lung cancer justified in patients over 70 years of age?

Paola Ciriaco, A. Puglisi, A. Carretta, B. Canneto, P. Zannini, A. Grossi

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Purpose: The aim of this study was to evaluate the benefit of surgery in patients >70 years of age with non-small cell lung cancer (NSCLC) in terms of postoperative complications, rehabilitation, and survival. Methods: Between January 1992 and January 1996, 75 patients, 64 men and 11 women, mean age 74.6 years (range 70-83), underwent surgical resection for primary NSCLC. At the time of admission 24 patients presented associated cardiovascular and/or respiratory problems (32%). Preoperative assessment included also echocardiography and/or miocardial scan in patients with concomitant cardiological problems. The six-minute walking test (6-MWT) was used in 21 patients at nigh risk for pulmonary resection. All patients had pulmonary rehabilitation. Pulmonary embolism was prevented with heparin and the use of a leg sequential pneumatic compression device. Postthoracotomy pain was managed using continuous epidural analgesia or patient controlled analgesia. Results: Preoperative FEV1%, FVC% and PaO2 were respectively 80% (range 48-97), 84% (range 58-100) and 87 mmHg (range 68-97) and influenced postoperative complications and survival (p70 years of age with NSCLC, should be given the opportunity of surgery provided that no major postoperative cardiorespiratory complication are foreseen. Clinical Implications: Careful preoperative evaluation, pulmonary rehabilitation and management of postoperative pain can reduce postoperative risk of cardiorespiratory failure.

Original languageEnglish
JournalChest
Volume110
Issue number4 SUPPL.
Publication statusPublished - Oct 1996

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Non-Small Cell Lung Carcinoma
Rehabilitation
Lung
Patient-Controlled Analgesia
Epidural Analgesia
Survival
Patient Admission
Postoperative Pain
Pulmonary Embolism
Walking
Echocardiography
Heparin
Leg
Pain
Equipment and Supplies

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Ciriaco, P., Puglisi, A., Carretta, A., Canneto, B., Zannini, P., & Grossi, A. (1996). Is surgery for non-small cell lung cancer justified in patients over 70 years of age? Chest, 110(4 SUPPL.).

Is surgery for non-small cell lung cancer justified in patients over 70 years of age? / Ciriaco, Paola; Puglisi, A.; Carretta, A.; Canneto, B.; Zannini, P.; Grossi, A.

In: Chest, Vol. 110, No. 4 SUPPL., 10.1996.

Research output: Contribution to journalArticle

Ciriaco, P, Puglisi, A, Carretta, A, Canneto, B, Zannini, P & Grossi, A 1996, 'Is surgery for non-small cell lung cancer justified in patients over 70 years of age?', Chest, vol. 110, no. 4 SUPPL..
Ciriaco P, Puglisi A, Carretta A, Canneto B, Zannini P, Grossi A. Is surgery for non-small cell lung cancer justified in patients over 70 years of age? Chest. 1996 Oct;110(4 SUPPL.).
Ciriaco, Paola ; Puglisi, A. ; Carretta, A. ; Canneto, B. ; Zannini, P. ; Grossi, A. / Is surgery for non-small cell lung cancer justified in patients over 70 years of age?. In: Chest. 1996 ; Vol. 110, No. 4 SUPPL.
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abstract = "Purpose: The aim of this study was to evaluate the benefit of surgery in patients >70 years of age with non-small cell lung cancer (NSCLC) in terms of postoperative complications, rehabilitation, and survival. Methods: Between January 1992 and January 1996, 75 patients, 64 men and 11 women, mean age 74.6 years (range 70-83), underwent surgical resection for primary NSCLC. At the time of admission 24 patients presented associated cardiovascular and/or respiratory problems (32{\%}). Preoperative assessment included also echocardiography and/or miocardial scan in patients with concomitant cardiological problems. The six-minute walking test (6-MWT) was used in 21 patients at nigh risk for pulmonary resection. All patients had pulmonary rehabilitation. Pulmonary embolism was prevented with heparin and the use of a leg sequential pneumatic compression device. Postthoracotomy pain was managed using continuous epidural analgesia or patient controlled analgesia. Results: Preoperative FEV1{\%}, FVC{\%} and PaO2 were respectively 80{\%} (range 48-97), 84{\%} (range 58-100) and 87 mmHg (range 68-97) and influenced postoperative complications and survival (p70 years of age with NSCLC, should be given the opportunity of surgery provided that no major postoperative cardiorespiratory complication are foreseen. Clinical Implications: Careful preoperative evaluation, pulmonary rehabilitation and management of postoperative pain can reduce postoperative risk of cardiorespiratory failure.",
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