Is there a real treatment for stroke? Clinical and statistical comparison of different treatments in 300 patients

Sergio Santambrogio, Renato Martinotti, Francesco Sardella, Fernando Porro, Antonio Randazzo

Research output: Contribution to journalArticle

Abstract

In the absence of universally accepted criteri a for the medical treatment of stroke, we made a rigorously randomized comparative study of different treatments in 300 patients. One group of patients received only a general supportive treatment designed to ensure adequate supplies of water, electrolytes and calories, plus whatever was needed to prevent infection and correct extant associated pathology. Three other groups of patients were treated in the same way but were also given, respectively, one of the following medications: Hydergine (Sandoz) (a mixture of three ergot alkaloids), dexamet hasone, and mannitol. No statistically significant differ ence emerged among any of the treatment groups and the reference group in terms of objective therapeutic results. The authors concluded that, at least with the dosage used in this study, none of the treatments proved more useful than conventional supportive therapy in the first 10 days after a stroke.

Original languageEnglish
Pages (from-to)130-132
Number of pages3
JournalStroke
Volume9
Issue number2
Publication statusPublished - 1978

    Fingerprint

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Clinical Neurology
  • Advanced and Specialised Nursing
  • Neuroscience(all)

Cite this

Santambrogio, S., Martinotti, R., Sardella, F., Porro, F., & Randazzo, A. (1978). Is there a real treatment for stroke? Clinical and statistical comparison of different treatments in 300 patients. Stroke, 9(2), 130-132.