Is there a role for immunotherapy in malignant pleural mesothelioma?

Alfredo Tartarone, Rosa Lerose, Michele Aieta

Research output: Contribution to journalReview article

Abstract

Malignant pleural mesothelioma (MPM) is a very aggressive malignancy, mainly caused by asbestos exposure. Patients with MPM have a poor prognosis that remained substantially unchanged in the last few years and limited effective therapeutic options with no recognized second or further-line therapy. In this context, also in view of the positive results observed in other tumor types, immunotherapy could play a relevant role. This review focuses on the most promising immunotherapies being investigated in MPM.

Original languageEnglish
Article number98
JournalMedical Oncology
Volume35
Issue number7
DOIs
Publication statusPublished - Jul 1 2018

Keywords

  • CAR T cell therapy
  • Immune checkpoint inhibitors
  • Immunotherapy
  • Malignant pleural mesothelioma

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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