Abstract
The debate regarding neurocognitive functions in the early stages of HIV infection is still ongoing; different studies have reached contrasting conclusions, probably because many of them take into account different cohorts of patients. A main distinction is between HIV seropositive patients infected perinatally, and those infected postnatally. The aim of this paper is to review results on neurocognitive dysfunctions and other types of neurological involvement in a specific cohort of HIV+ patients infected postnatally: hemophilia patients. Such a review is relevant, as HIV seropositive patients infected postnatally are understudied with respect to patients infected perinatally, and as the results of the few studies aiming at comparing them are contrasting. Taken together, the 11 studies reviewed suggest the presence of both long-term neurocognitive dysfunctions and neurological alterations, such as the presence of atrophic changes and lesions in the white matter. The current review may offer new research insights into the neurocognitive dysfunctions in HIV-patients, and on the nature of such dysfunctions.
| Original language | English |
|---|---|
| Article number | 470 |
| Journal | Frontiers in Human Neuroscience |
| Volume | 8 |
| Issue number | JUNE |
| DOIs | |
| Publication status | Published - Jun 24 2014 |
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Keywords
- Assessment
- Cognitive test
- Hemophilia
- HIV
- Neurocognitive dysfunctions
- Postnatally infection
ASJC Scopus subject areas
- Psychiatry and Mental health
- Neurology
- Biological Psychiatry
- Behavioral Neuroscience
- Neuropsychology and Physiological Psychology
Cite this
Is there evidence for neurocognitive dysfunctions in patients with postnatal HIV infection? A review on the cohort of hemophilia patients. / Riva, Silvia; Cutica, Ilaria; Pravettoni, Gabriella.
In: Frontiers in Human Neuroscience, Vol. 8, No. JUNE, 470, 24.06.2014.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Is there evidence for neurocognitive dysfunctions in patients with postnatal HIV infection? A review on the cohort of hemophilia patients
AU - Riva, Silvia
AU - Cutica, Ilaria
AU - Pravettoni, Gabriella
PY - 2014/6/24
Y1 - 2014/6/24
N2 - The debate regarding neurocognitive functions in the early stages of HIV infection is still ongoing; different studies have reached contrasting conclusions, probably because many of them take into account different cohorts of patients. A main distinction is between HIV seropositive patients infected perinatally, and those infected postnatally. The aim of this paper is to review results on neurocognitive dysfunctions and other types of neurological involvement in a specific cohort of HIV+ patients infected postnatally: hemophilia patients. Such a review is relevant, as HIV seropositive patients infected postnatally are understudied with respect to patients infected perinatally, and as the results of the few studies aiming at comparing them are contrasting. Taken together, the 11 studies reviewed suggest the presence of both long-term neurocognitive dysfunctions and neurological alterations, such as the presence of atrophic changes and lesions in the white matter. The current review may offer new research insights into the neurocognitive dysfunctions in HIV-patients, and on the nature of such dysfunctions.
AB - The debate regarding neurocognitive functions in the early stages of HIV infection is still ongoing; different studies have reached contrasting conclusions, probably because many of them take into account different cohorts of patients. A main distinction is between HIV seropositive patients infected perinatally, and those infected postnatally. The aim of this paper is to review results on neurocognitive dysfunctions and other types of neurological involvement in a specific cohort of HIV+ patients infected postnatally: hemophilia patients. Such a review is relevant, as HIV seropositive patients infected postnatally are understudied with respect to patients infected perinatally, and as the results of the few studies aiming at comparing them are contrasting. Taken together, the 11 studies reviewed suggest the presence of both long-term neurocognitive dysfunctions and neurological alterations, such as the presence of atrophic changes and lesions in the white matter. The current review may offer new research insights into the neurocognitive dysfunctions in HIV-patients, and on the nature of such dysfunctions.
KW - Assessment
KW - Cognitive test
KW - Hemophilia
KW - HIV
KW - Neurocognitive dysfunctions
KW - Postnatally infection
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U2 - 10.3389/fnhum.2014.00470
DO - 10.3389/fnhum.2014.00470
M3 - Article
AN - SCOPUS:84930671219
VL - 8
JO - Frontiers in Human Neuroscience
JF - Frontiers in Human Neuroscience
SN - 1662-5161
IS - JUNE
M1 - 470
ER -