Is unicondylar osteoarticular allograft still a viable option for reconstructions around the knee?

G. Bianchi, Andrea Sambri, E. Sebastiani, E. Caldari, D. M. Donati

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Unicondylar osteoarticular allografts (UOAs) represent a possible technique for reconstructing massive bone defects around the knee when only one condyle is affected. The aim of this retrospective study is to evaluate the outcome of UOAs and describe the possible salvage procedures in case of graft failure. Methods: Twenty-five deep-frozen UOAs were implanted at Rizzoli Orthopedic Institute (Bologna, Italy). Twenty-two followed bone tumor resection, two cases were post-traumatic defects and one case followed UOA failure.Mean age at surgery was 33. years (range: 15 to 63). Eighteen UOAs were in distal femur, seven in proximal tibia. Results: Three patients died (only one because of the tumor). One UOA was removed for chondrosarcoma relapse and one for allograft fracture. Mean overall survival with UOA failure as a primary endpoint was 129. months (range 12 to 302), with differences in the femur (85%) and in the tibia (40%) at 150. months. Six UOAs had to be converted into knee prostheses due to osteoarthritis after a mean follow-up of 146. months. No complications were recorded in UOAs converted into knee prostheses after a mean three year follow-up. Fourteen patients with UOAs still in place at the last follow-up (mean 123. months) were radiologically and functionally evaluated: no correlation was found between function and the degree of osteoarthritis. Conclusions: In selected cases, UOAs offer good clinical results and postpone the need for knee prosthesis. Despite short-term encouraging results, longer-term follow-up is needed in order to evaluate the outcome of knee prosthesis after UOA.

Original languageEnglish
JournalKnee
DOIs
Publication statusAccepted/In press - Nov 23 2015

Fingerprint

Allografts
Knee
Knee Prosthesis
Tibia
Bone and Bones
Osteoarthritis
Femur
Chondrosarcoma
Italy
Orthopedics
Neoplasms
Retrospective Studies
Transplants
Recurrence
Survival

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Is unicondylar osteoarticular allograft still a viable option for reconstructions around the knee? / Bianchi, G.; Sambri, Andrea; Sebastiani, E.; Caldari, E.; Donati, D. M.

In: Knee, 23.11.2015.

Research output: Contribution to journalArticle

@article{6ccb711d7982493598a8385bf56ea84e,
title = "Is unicondylar osteoarticular allograft still a viable option for reconstructions around the knee?",
abstract = "Background: Unicondylar osteoarticular allografts (UOAs) represent a possible technique for reconstructing massive bone defects around the knee when only one condyle is affected. The aim of this retrospective study is to evaluate the outcome of UOAs and describe the possible salvage procedures in case of graft failure. Methods: Twenty-five deep-frozen UOAs were implanted at Rizzoli Orthopedic Institute (Bologna, Italy). Twenty-two followed bone tumor resection, two cases were post-traumatic defects and one case followed UOA failure.Mean age at surgery was 33. years (range: 15 to 63). Eighteen UOAs were in distal femur, seven in proximal tibia. Results: Three patients died (only one because of the tumor). One UOA was removed for chondrosarcoma relapse and one for allograft fracture. Mean overall survival with UOA failure as a primary endpoint was 129. months (range 12 to 302), with differences in the femur (85{\%}) and in the tibia (40{\%}) at 150. months. Six UOAs had to be converted into knee prostheses due to osteoarthritis after a mean follow-up of 146. months. No complications were recorded in UOAs converted into knee prostheses after a mean three year follow-up. Fourteen patients with UOAs still in place at the last follow-up (mean 123. months) were radiologically and functionally evaluated: no correlation was found between function and the degree of osteoarthritis. Conclusions: In selected cases, UOAs offer good clinical results and postpone the need for knee prosthesis. Despite short-term encouraging results, longer-term follow-up is needed in order to evaluate the outcome of knee prosthesis after UOA.",
author = "G. Bianchi and Andrea Sambri and E. Sebastiani and E. Caldari and Donati, {D. M.}",
year = "2015",
month = "11",
day = "23",
doi = "10.1016/j.knee.2016.03.002",
language = "English",
journal = "Knee",
issn = "0968-0160",
publisher = "Elsevier",

}

TY - JOUR

T1 - Is unicondylar osteoarticular allograft still a viable option for reconstructions around the knee?

AU - Bianchi, G.

AU - Sambri, Andrea

AU - Sebastiani, E.

AU - Caldari, E.

AU - Donati, D. M.

PY - 2015/11/23

Y1 - 2015/11/23

N2 - Background: Unicondylar osteoarticular allografts (UOAs) represent a possible technique for reconstructing massive bone defects around the knee when only one condyle is affected. The aim of this retrospective study is to evaluate the outcome of UOAs and describe the possible salvage procedures in case of graft failure. Methods: Twenty-five deep-frozen UOAs were implanted at Rizzoli Orthopedic Institute (Bologna, Italy). Twenty-two followed bone tumor resection, two cases were post-traumatic defects and one case followed UOA failure.Mean age at surgery was 33. years (range: 15 to 63). Eighteen UOAs were in distal femur, seven in proximal tibia. Results: Three patients died (only one because of the tumor). One UOA was removed for chondrosarcoma relapse and one for allograft fracture. Mean overall survival with UOA failure as a primary endpoint was 129. months (range 12 to 302), with differences in the femur (85%) and in the tibia (40%) at 150. months. Six UOAs had to be converted into knee prostheses due to osteoarthritis after a mean follow-up of 146. months. No complications were recorded in UOAs converted into knee prostheses after a mean three year follow-up. Fourteen patients with UOAs still in place at the last follow-up (mean 123. months) were radiologically and functionally evaluated: no correlation was found between function and the degree of osteoarthritis. Conclusions: In selected cases, UOAs offer good clinical results and postpone the need for knee prosthesis. Despite short-term encouraging results, longer-term follow-up is needed in order to evaluate the outcome of knee prosthesis after UOA.

AB - Background: Unicondylar osteoarticular allografts (UOAs) represent a possible technique for reconstructing massive bone defects around the knee when only one condyle is affected. The aim of this retrospective study is to evaluate the outcome of UOAs and describe the possible salvage procedures in case of graft failure. Methods: Twenty-five deep-frozen UOAs were implanted at Rizzoli Orthopedic Institute (Bologna, Italy). Twenty-two followed bone tumor resection, two cases were post-traumatic defects and one case followed UOA failure.Mean age at surgery was 33. years (range: 15 to 63). Eighteen UOAs were in distal femur, seven in proximal tibia. Results: Three patients died (only one because of the tumor). One UOA was removed for chondrosarcoma relapse and one for allograft fracture. Mean overall survival with UOA failure as a primary endpoint was 129. months (range 12 to 302), with differences in the femur (85%) and in the tibia (40%) at 150. months. Six UOAs had to be converted into knee prostheses due to osteoarthritis after a mean follow-up of 146. months. No complications were recorded in UOAs converted into knee prostheses after a mean three year follow-up. Fourteen patients with UOAs still in place at the last follow-up (mean 123. months) were radiologically and functionally evaluated: no correlation was found between function and the degree of osteoarthritis. Conclusions: In selected cases, UOAs offer good clinical results and postpone the need for knee prosthesis. Despite short-term encouraging results, longer-term follow-up is needed in order to evaluate the outcome of knee prosthesis after UOA.

UR - http://www.scopus.com/inward/record.url?scp=84964811113&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84964811113&partnerID=8YFLogxK

U2 - 10.1016/j.knee.2016.03.002

DO - 10.1016/j.knee.2016.03.002

M3 - Article

AN - SCOPUS:84964811113

JO - Knee

JF - Knee

SN - 0968-0160

ER -