Abstract
The association of white-coat hypertension (WCH) with target organ damage is still debated; in particular, the relationship of this blood pressure phenotype with subclinical vascular damage remains controversial. Thus, we carried out a systematic review and meta-analysis to provide updated information on carotid structural changes in WCH. Studies were identified using the following search terms: 'white coat hypertension', 'isolated clinic hypertension', 'carotid artery', 'carotid atherosclerosis', 'carotid intima-media thickness', 'carotid damage', 'carotid thickening'. Full articles published in the English language in the last two decades reporting studies on adults were considered. A total of 3478 untreated patients, 940 normotensive (48% men), 666 WCH (48% men), and 1872 hypertensive individuals (57% men) included in 10 studies, were analyzed. Common carotid intima-media thickness (IMT) showed a progressive increase from normotensive (718± 36 μm) to WCH (763± 47 μm, standardized mean difference 0.54 ±0.13, P
Original language | English |
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Pages (from-to) | 57-63 |
Number of pages | 7 |
Journal | Blood Pressure Monitoring |
Volume | 20 |
Issue number | 2 |
DOIs | |
Publication status | Published - Mar 27 2015 |
Keywords
- ambulatory blood pressure monitoring
- carotid intima-media thickness
- white-coat hypertension
ASJC Scopus subject areas
- Internal Medicine
- Cardiology and Cardiovascular Medicine
- Assessment and Diagnosis
- Advanced and Specialised Nursing
- Medicine(all)