Abstract
Objective: To assess the influence of vascular clamping and ischemia time on long-term post-operative renal function following partial nephrectomy (PN) for cancer in a solitary kidney. Patients and methods: This is a retrospective study including 259patients managed by PN between 1979 and 2010 in 13centers. Clamping use, technique choice (pedicular or parenchymal clamping), ischemia time, and peri-operative data were collected. Pre-operative and last follow-up glomerular filtration rates were compared. A multivariate analysis using a Cox model was performed to assess the impact of ischemia on post-operative chronic renal failure risk. Results: Mean tumor size was 4.0. ±. 2.3. cm and mean pre-operative glomerular filtration rate was 60.8. ±. 18.9. mL/min. One hundred and six patients were managed with warm ischemia (40.9%) and 53patients with cold ischemia (20.5%). Thirty patients (11.6%) have had a chronic kidney disease. In multivariate analysis, neither vascular clamping (P= 0.44) nor warm ischemia time (P= 0.1) were associated with a pejorative evolution of renal function. Pre-operative glomerular filtration rate (P
Translated title of the contribution | Ischemia is not an independent predictive factor of chronic renal failure after partial nephrectomy in a solitary kidney in patients without pre-operative renal insufficiency |
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Original language | French |
Pages (from-to) | 27-33 |
Number of pages | 7 |
Journal | Progres en Urologie |
Volume | 25 |
Issue number | 1 |
DOIs | |
Publication status | Published - Jan 1 2015 |
Keywords
- Nephron-sparing surgery
- Partial nephrectomy
- Renal function
- Solitary kidney
ASJC Scopus subject areas
- Urology
- Medicine(all)