L'ischémie a un impact limité sur la fonction rénale après néphrectomie partielle sur rein unique chez les patients sans insuffisance rénale préopératoire

Translated title of the contribution: Ischemia is not an independent predictive factor of chronic renal failure after partial nephrectomy in a solitary kidney in patients without pre-operative renal insufficiency

R. Bahi, G. Pignot, Y. Hammoudi, K. Bensalah, E. Oger, P. Laguna, K. Barwari, T. Bessède, J. Rigaud, M. Roupret, J. C. Bernhard, J. A. Long, A. Zisman, J. Berger, P. Paparel, E. Lechevallier, R. Bertini, L. Salomon, A. Bex, R. FarfaraB. Ljungberg, A. R. Rodriguez, J. J. Patard

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To assess the influence of vascular clamping and ischemia time on long-term post-operative renal function following partial nephrectomy (PN) for cancer in a solitary kidney. Patients and methods: This is a retrospective study including 259patients managed by PN between 1979 and 2010 in 13centers. Clamping use, technique choice (pedicular or parenchymal clamping), ischemia time, and peri-operative data were collected. Pre-operative and last follow-up glomerular filtration rates were compared. A multivariate analysis using a Cox model was performed to assess the impact of ischemia on post-operative chronic renal failure risk. Results: Mean tumor size was 4.0. ±. 2.3. cm and mean pre-operative glomerular filtration rate was 60.8. ±. 18.9. mL/min. One hundred and six patients were managed with warm ischemia (40.9%) and 53patients with cold ischemia (20.5%). Thirty patients (11.6%) have had a chronic kidney disease. In multivariate analysis, neither vascular clamping (P= 0.44) nor warm ischemia time (P= 0.1) were associated with a pejorative evolution of renal function. Pre-operative glomerular filtration rate (P

Translated title of the contributionIschemia is not an independent predictive factor of chronic renal failure after partial nephrectomy in a solitary kidney in patients without pre-operative renal insufficiency
Original languageFrench
Pages (from-to)27-33
Number of pages7
JournalProgres en Urologie
Volume25
Issue number1
DOIs
Publication statusPublished - Jan 1 2015

Keywords

  • Nephron-sparing surgery
  • Partial nephrectomy
  • Renal function
  • Solitary kidney

ASJC Scopus subject areas

  • Urology
  • Medicine(all)

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