Ischemic heart disease in systemic inflammatory diseases. An appraisal

Paola Gargiulo, Fabio Marsico, Antonio Parente, Stefania Paolillo, Milena Cecere, Laura Casaretti, Angela Maria Pellegrino, Tiziana Formisano, Irma Fabiani, Andrea Soricelli, Bruno Trimarco, Pasquale Perrone-Filardi

Research output: Contribution to journalArticlepeer-review


Systemic inflammatory diseases are inflammatory syndromes that are associated with increased cardiovascular morbidity and mortality. The link between inflammatory and cardiovascular diseases can be attributed to coexistence of classical risk factors and of inflammatory mechanisms activated in systemic inflammatory diseases and involving the immune system. Yet, clinical implications of these findings are not entirely clear and deeper knowledge and awareness of cardiac involvement in inflammatory diseases are necessary. The aims of this review are to summarize cardiac involvement in systemic inflammatory diseases and to identify areas where evidence is currently lacking that deserve further investigation in the future.

Original languageEnglish
Pages (from-to)286-290
Number of pages5
JournalInternational Journal of Cardiology
Issue number3
Publication statusPublished - Jan 1 2014


  • Atherosclerosis
  • Coronary artery disease
  • Immune system
  • Systemic inflammatory disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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