Islet transplantation improves vascular diabetic complications in patients with diabetes who underwent kidney transplantation: A comparison between kidney-pancreas and kidney-alone transplantation

Paolo Fiorina, Franco Folli, Paola Maffi, Claudia Placidi, Massimo Venturini, Giovanna Finzi, Federico Bertuzzi, Alberto Davalli, Armando D'Angelo, Carlo Socci, Chiara Gremizzi, Elena Orsenigo, Stefano La Rosa, Maurilio Ponzoni, Massimo Cardillo, Mario Scalamogna, Alessandro Del Maschio, Carlo Capella, Valerio Di Carlo, Antonio Secchi

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Abstract

Background. The aim of this study was to evaluate the effects of islet transplantation on patient survival and diabetic vascular complications. Methods. Thirty-seven type 1 uremic diabetic kidney transplant patients underwent islet transplantation (KI group). Uremic type 1 diabetic kidney-pancreas (KP group, n=162), kidney-alone (KD group, n=42) transplant patients, and uremic type 1 diabetic patients still on hemodialysis (HD+DM group, n=196) constituted the control groups for survival and endothelial morphology. Results. Patient survival was similar in the KI and KP groups and higher than in the HD+DM group (P

Original languageEnglish
Pages (from-to)1296-1301
Number of pages6
JournalTransplantation
Volume75
Issue number8
DOIs
Publication statusPublished - Apr 27 2003

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ASJC Scopus subject areas

  • Transplantation
  • Immunology

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