Abstract
We report a case of herpetic brainstem encephalitis (HBE) retrospectively diagnosed in an adult patient. Conventional immunovirological studies failed to disclose the etiology of this patient's affection. An isoelectric focusing-antigen overlay (IEF-O) technique showed that the target of one of the four cerebrospinal fluid oligoclonal bands was herpes simplex virus (HSV)-1 glycoprotein B, indicating a specific anti-HSV immunoresponse restricted to the CNS. IEF-O may represent a useful support for in vivo diagnosis of HBE.
Original language | English |
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Pages (from-to) | 364-367 |
Number of pages | 4 |
Journal | Acta Neurologica Scandinavica |
Volume | 82 |
Issue number | 6 |
Publication status | Published - 1990 |
Keywords
- brainstem encephalitis
- herpes simplex virus type 1
- isoelectric focusing antigen overlay
- oligoclonal bands
ASJC Scopus subject areas
- Clinical Neurology
- Neuroscience(all)