Isolated brain metastasis of malignant choroidal melanoma 27 years after enucleation

Edoardo Midena, Valentina De Belvis, Angela P. Dei Tos, Cristina Antonini

Research output: Contribution to journalArticle

Abstract

Choroidal melanoma primarily metastasizes to the liver. Isolated extrahepatic metastases have rarely been reported and they generally resulted in death within 6 months. We describe a patient who developed an isolated brain metastasis 27 years after his left eye was enucleated for choroidal melanoma. The metastasis was successfully treated with surgery and radiotherapy. The patient is alive and disease free 3 years after treatment of the metastasis. Posterior location and other clinical and morphologic characteristics of primary choroidal melanoma could explain the unusually long latency of this solitary extrahepatic metastatic disease. Lifelong surveillance to detect early signs of metastasis is mandatory for any patient treated for choroidal melanoma.

Original languageEnglish
Pages (from-to)1553-1556
Number of pages4
JournalArchives of Ophthalmology
Volume117
Issue number11
Publication statusPublished - Nov 1999

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Melanoma
Neoplasm Metastasis
Brain
Radiotherapy
Liver
Therapeutics

ASJC Scopus subject areas

  • Ophthalmology

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Midena, E., De Belvis, V., Dei Tos, A. P., & Antonini, C. (1999). Isolated brain metastasis of malignant choroidal melanoma 27 years after enucleation. Archives of Ophthalmology, 117(11), 1553-1556.

Isolated brain metastasis of malignant choroidal melanoma 27 years after enucleation. / Midena, Edoardo; De Belvis, Valentina; Dei Tos, Angela P.; Antonini, Cristina.

In: Archives of Ophthalmology, Vol. 117, No. 11, 11.1999, p. 1553-1556.

Research output: Contribution to journalArticle

Midena, E, De Belvis, V, Dei Tos, AP & Antonini, C 1999, 'Isolated brain metastasis of malignant choroidal melanoma 27 years after enucleation', Archives of Ophthalmology, vol. 117, no. 11, pp. 1553-1556.
Midena, Edoardo ; De Belvis, Valentina ; Dei Tos, Angela P. ; Antonini, Cristina. / Isolated brain metastasis of malignant choroidal melanoma 27 years after enucleation. In: Archives of Ophthalmology. 1999 ; Vol. 117, No. 11. pp. 1553-1556.
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