Isolated Degenerative Amnesia Without Dementia: An 8-year Longitudinal Study

Paolo Caffarra, Annalena Venneri

Research output: Contribution to journalArticlepeer-review


A case of a 72-year-old patient suffering from progressive isolated memory disorders is reported. The patient has been followed up over eight years and her neuropsychological profile reveals a high standard of performance on all tests assessing intelligence, language, praxis, attention, and short-term memory, but she fails all long-term memory tasks. MRI images showed bilateral hippocampal atrophy in the sagittal and coronal sections in the absence of white matter signal abnormalities. [18FDG] PET scan detected bilateral hypometabolism of the hippocampal regions and of the thalamus and mild metabolic reduction in the frontal area. The neuroimaging and neuropsychological profiles point to a progressive amnesia of degenerative aetiology.

Original languageEnglish
Pages (from-to)99-106
Number of pages8
Issue number2
Publication statusPublished - 1996

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Neurology
  • Psychology(all)


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