Isolated Liver Transplantation in an Infant With Ultrashort Gut

A. Lezo, F. Gennari, B. Santini, P. Calvo, M. Baldi, M. Salizzoni, C. Barbera, J. B. Otte, J. de Ville de Goyet

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Intestinal function in children with very short bowel syndrome and related intestinal failure may improve after isolated liver transplantation. An infant with an ultrashort gut, ileo-cecal valve, and whole colon received total parenteral nutrition from the first days of life. Enteral feeding failed because of the progressive dilatation of the jejunal portion and motility disorders. He developed early severe cholestatic liver disease (aspartate transferase 186, alanine transferase 103 U/L, serum bilirubin 8.4 mg/dL) and subsequent liver failure. At 8 months of age, he benefited from isolated liver transplantation (left segment graft from living donor). His early posttransplant evolution was characterized by recovery of oral alimentation, improvement of digestive and absorption functions, but he did not achieve TPN-independence. At 20 months, 50% to 60% of his energy needs were covered by parenteral nutrition and he has satisfactory growth indices (3rd percentile for weight and height), reduced stool volume, and frequency. Isolated liver transplantation allowed, in this particular case, time for further intestinal adaptation thereby avoiding the need for intestinal transplantation early in life.

Original languageEnglish
Pages (from-to)1713-1715
Number of pages3
JournalTransplantation Proceedings
Volume38
Issue number6
DOIs
Publication statusPublished - Jul 2006

Fingerprint

Liver Transplantation
Transferases
Short Bowel Syndrome
Total Parenteral Nutrition
Living Donors
Parenteral Nutrition
Liver Failure
Enteral Nutrition
Bilirubin
Aspartic Acid
Alanine
Liver Diseases
Dilatation
Colon
Transplantation
Transplants
Weights and Measures
Growth
Serum

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Lezo, A., Gennari, F., Santini, B., Calvo, P., Baldi, M., Salizzoni, M., ... de Ville de Goyet, J. (2006). Isolated Liver Transplantation in an Infant With Ultrashort Gut. Transplantation Proceedings, 38(6), 1713-1715. https://doi.org/10.1016/j.transproceed.2006.05.045

Isolated Liver Transplantation in an Infant With Ultrashort Gut. / Lezo, A.; Gennari, F.; Santini, B.; Calvo, P.; Baldi, M.; Salizzoni, M.; Barbera, C.; Otte, J. B.; de Ville de Goyet, J.

In: Transplantation Proceedings, Vol. 38, No. 6, 07.2006, p. 1713-1715.

Research output: Contribution to journalArticle

Lezo, A, Gennari, F, Santini, B, Calvo, P, Baldi, M, Salizzoni, M, Barbera, C, Otte, JB & de Ville de Goyet, J 2006, 'Isolated Liver Transplantation in an Infant With Ultrashort Gut', Transplantation Proceedings, vol. 38, no. 6, pp. 1713-1715. https://doi.org/10.1016/j.transproceed.2006.05.045
Lezo A, Gennari F, Santini B, Calvo P, Baldi M, Salizzoni M et al. Isolated Liver Transplantation in an Infant With Ultrashort Gut. Transplantation Proceedings. 2006 Jul;38(6):1713-1715. https://doi.org/10.1016/j.transproceed.2006.05.045
Lezo, A. ; Gennari, F. ; Santini, B. ; Calvo, P. ; Baldi, M. ; Salizzoni, M. ; Barbera, C. ; Otte, J. B. ; de Ville de Goyet, J. / Isolated Liver Transplantation in an Infant With Ultrashort Gut. In: Transplantation Proceedings. 2006 ; Vol. 38, No. 6. pp. 1713-1715.
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