Isolated Liver Transplantation in an Infant With Ultrashort Gut

A. Lezo, F. Gennari, B. Santini, P. Calvo, M. Baldi, M. Salizzoni, C. Barbera, J. B. Otte, J. de Ville de Goyet

Research output: Contribution to journalArticlepeer-review


Intestinal function in children with very short bowel syndrome and related intestinal failure may improve after isolated liver transplantation. An infant with an ultrashort gut, ileo-cecal valve, and whole colon received total parenteral nutrition from the first days of life. Enteral feeding failed because of the progressive dilatation of the jejunal portion and motility disorders. He developed early severe cholestatic liver disease (aspartate transferase 186, alanine transferase 103 U/L, serum bilirubin 8.4 mg/dL) and subsequent liver failure. At 8 months of age, he benefited from isolated liver transplantation (left segment graft from living donor). His early posttransplant evolution was characterized by recovery of oral alimentation, improvement of digestive and absorption functions, but he did not achieve TPN-independence. At 20 months, 50% to 60% of his energy needs were covered by parenteral nutrition and he has satisfactory growth indices (3rd percentile for weight and height), reduced stool volume, and frequency. Isolated liver transplantation allowed, in this particular case, time for further intestinal adaptation thereby avoiding the need for intestinal transplantation early in life.

Original languageEnglish
Pages (from-to)1713-1715
Number of pages3
JournalTransplantation Proceedings
Issue number6
Publication statusPublished - Jul 2006

ASJC Scopus subject areas

  • Surgery
  • Transplantation


Dive into the research topics of 'Isolated Liver Transplantation in an Infant With Ultrashort Gut'. Together they form a unique fingerprint.

Cite this