Isolated rat hepatocytes as a tool for the determination of antibodies against human liver cell membrane

F. Autuori, E. Capucci, L. Conti Devirgiliis, C. Di Giacomo, L. Dini, G. Marinucci

Research output: Contribution to journalArticlepeer-review

Abstract

Antibodies against liver cell membrane are measured by counting the percentages of fluorescent rat hepatocytes (FRH), obtained by an indirect immunofluorescence method after incubation of isolated rat hepatocytes with sera of patients with chronic liver diseases. A close relationship exists between the percentages of FRH and the serological and histological parameters of diseases activity, there was no difference between HBsAg-positive or -negative sera.

Original languageEnglish
Pages (from-to)458-461
Number of pages4
JournalBiomedicine and Pharmacotherapy
Volume37
Issue number9-10
Publication statusPublished - 1983

ASJC Scopus subject areas

  • Pharmacology

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