Isolation and cloning by a polymerase chain reaction of a genomic DNA fragment of the human slow skeletal troponin (TNNT1) gene

G. Novelli, M. Gennarelli, F. Sangiuolo, L. D'Agruma, S. Lo Cicero, S. Melchionda, B. Dallapiccola

Research output: Contribution to journalArticle

Abstract

The genomic 3' structure of the gene coding for the human slow skeletal troponin T (TNNT1) gene, is reported. An intron of 912 nucleotides containing an Alu-element has been identified and characterized. The complexity of the sequenced region suggests an alternative exon use. The present results may be valuable for further studies on the gene structure of TNNT1 and the related troponin gene family.

Original languageEnglish
Pages (from-to)187-191
Number of pages5
JournalCell Biochemistry and Function
Volume11
Issue number3
Publication statusPublished - 1993

Keywords

  • Alu sequences
  • Polymerase chain reaction
  • Troponin T

ASJC Scopus subject areas

  • Cell Biology
  • Clinical Biochemistry

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