Isolation and molecular characterization of Candida africana from Jos, Nigeria

Nnaemeka Emmanuel Nnadi, Grace Mebi Ayanbimpe, Fabio Scordino, Mark Ojogba Okolo, Ifeoma Bessy Enweani, Giuseppe Criseo, Orazio Romeo

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

During a survey of the prevalence of Candida spp. in Jos, Plateau State, Nigeria, two atypical C. albicans isolates were recovered. These two yeasts were germ tube positive, chlamydospore-negative and gave a green color on CHROMagar Candida. Molecular analysis performed by amplification of the hwp1 gene showed that these two isolates belonged to C. africana, a newly proposed Candida species closely related to C. albicans. Based on the presence or absence of an intron in DNA sequences encoding rRNA, the two C. africana, including all C. albicans isolates examined, were found to belong to genotype A and no other genotypes or species such as C. dubliniensis were found. To our knowledge, this is the first isolation of C. africana in Nigeria.

Original languageEnglish
Pages (from-to)765-767
Number of pages3
JournalMedical Mycology
Volume50
Issue number7
DOIs
Publication statusPublished - Oct 2012

Fingerprint

Nigeria
Candida
Candida albicans
Genotype
chlamydospores
germ tube
Gene Amplification
genotype
Introns
introns
plateaus
Color
Yeasts
polymerase chain reaction
ribosomal RNA
yeasts
nucleotide sequences
color

Keywords

  • Candida africana
  • Candida albicans
  • Candida dubliniensis
  • Chlamydospore-negative
  • Hwp1 gene

ASJC Scopus subject areas

  • veterinary(all)
  • Infectious Diseases

Cite this

Nnadi, N. E., Ayanbimpe, G. M., Scordino, F., Okolo, M. O., Enweani, I. B., Criseo, G., & Romeo, O. (2012). Isolation and molecular characterization of Candida africana from Jos, Nigeria. Medical Mycology, 50(7), 765-767. https://doi.org/10.3109/13693786.2012.662598

Isolation and molecular characterization of Candida africana from Jos, Nigeria. / Nnadi, Nnaemeka Emmanuel; Ayanbimpe, Grace Mebi; Scordino, Fabio; Okolo, Mark Ojogba; Enweani, Ifeoma Bessy; Criseo, Giuseppe; Romeo, Orazio.

In: Medical Mycology, Vol. 50, No. 7, 10.2012, p. 765-767.

Research output: Contribution to journalArticle

Nnadi, NE, Ayanbimpe, GM, Scordino, F, Okolo, MO, Enweani, IB, Criseo, G & Romeo, O 2012, 'Isolation and molecular characterization of Candida africana from Jos, Nigeria', Medical Mycology, vol. 50, no. 7, pp. 765-767. https://doi.org/10.3109/13693786.2012.662598
Nnadi NE, Ayanbimpe GM, Scordino F, Okolo MO, Enweani IB, Criseo G et al. Isolation and molecular characterization of Candida africana from Jos, Nigeria. Medical Mycology. 2012 Oct;50(7):765-767. https://doi.org/10.3109/13693786.2012.662598
Nnadi, Nnaemeka Emmanuel ; Ayanbimpe, Grace Mebi ; Scordino, Fabio ; Okolo, Mark Ojogba ; Enweani, Ifeoma Bessy ; Criseo, Giuseppe ; Romeo, Orazio. / Isolation and molecular characterization of Candida africana from Jos, Nigeria. In: Medical Mycology. 2012 ; Vol. 50, No. 7. pp. 765-767.
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