TY - JOUR
T1 - Isolation and molecular characterization of Candida africana from Jos, Nigeria
AU - Nnadi, Nnaemeka Emmanuel
AU - Ayanbimpe, Grace Mebi
AU - Scordino, Fabio
AU - Okolo, Mark Ojogba
AU - Enweani, Ifeoma Bessy
AU - Criseo, Giuseppe
AU - Romeo, Orazio
PY - 2012/10
Y1 - 2012/10
N2 - During a survey of the prevalence of Candida spp. in Jos, Plateau State, Nigeria, two atypical C. albicans isolates were recovered. These two yeasts were germ tube positive, chlamydospore-negative and gave a green color on CHROMagar Candida. Molecular analysis performed by amplification of the hwp1 gene showed that these two isolates belonged to C. africana, a newly proposed Candida species closely related to C. albicans. Based on the presence or absence of an intron in DNA sequences encoding rRNA, the two C. africana, including all C. albicans isolates examined, were found to belong to genotype A and no other genotypes or species such as C. dubliniensis were found. To our knowledge, this is the first isolation of C. africana in Nigeria.
AB - During a survey of the prevalence of Candida spp. in Jos, Plateau State, Nigeria, two atypical C. albicans isolates were recovered. These two yeasts were germ tube positive, chlamydospore-negative and gave a green color on CHROMagar Candida. Molecular analysis performed by amplification of the hwp1 gene showed that these two isolates belonged to C. africana, a newly proposed Candida species closely related to C. albicans. Based on the presence or absence of an intron in DNA sequences encoding rRNA, the two C. africana, including all C. albicans isolates examined, were found to belong to genotype A and no other genotypes or species such as C. dubliniensis were found. To our knowledge, this is the first isolation of C. africana in Nigeria.
KW - Candida africana
KW - Candida albicans
KW - Candida dubliniensis
KW - Chlamydospore-negative
KW - Hwp1 gene
UR - http://www.scopus.com/inward/record.url?scp=84866504859&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84866504859&partnerID=8YFLogxK
U2 - 10.3109/13693786.2012.662598
DO - 10.3109/13693786.2012.662598
M3 - Article
C2 - 22380533
AN - SCOPUS:84866504859
VL - 50
SP - 765
EP - 767
JO - Medical Mycology
JF - Medical Mycology
SN - 1369-3786
IS - 7
ER -