Isolation and morphological characterisation of UHMWPE wear debris generated in vitro

S. Affatato, B. Fernandes, A. Tucci, L. Esposito, A. Toni

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Wear tests are generally carried out on materials used in prosthetic hip implants, in order to obtain a better understanding of the tribological processes involved and improve the quality control of joint prostheses, directed towards reducing the risk of implant failure of innovative prostheses. Ceramic femoral heads of mixed alumina-zirconia oxides as well as zirconia and alumina single oxide heads were tested against UHMWPE acetabular cups in a hip joint simulator. Polyethylene cups and ceramic femoral heads were mounted in a simulator apparatus moving according to a sinusoidal function, under load and in the presence of bovine calf serum as lubricant. Wear particles were isolated from the bovine calf serum collected during the wear tests. An easy to follow method was used to separate the wear particles from the lubricant. Chemical digestive methods were used to separate the wear particles from the lubricant and the isolated particles were studied using scanning electron microscopy. The morphologies of the polyethylene debris showed considerable differences, both in size and shape of the particles, as a function of the coupled head material.

Original languageEnglish
Pages (from-to)2325-2331
Number of pages7
JournalBiomaterials
Volume22
Issue number17
DOIs
Publication statusPublished - 2001

Fingerprint

Lubricants
Ultrahigh molecular weight polyethylenes
Debris
Aluminum Oxide
Wear of materials
Ceramics
Polyethylene
Thigh
Joint Prosthesis
Prosthesis Failure
Prosthetics
Zirconia
Hip Joint
Polyethylenes
Serum
Particle Size
Alumina
Quality Control
Electron Scanning Microscopy
Oxides

Keywords

  • Hip joint simulator
  • Polyethylene debris isolation
  • Polyethylene wear debris
  • Zirconia-based ceramics

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

Cite this

Isolation and morphological characterisation of UHMWPE wear debris generated in vitro. / Affatato, S.; Fernandes, B.; Tucci, A.; Esposito, L.; Toni, A.

In: Biomaterials, Vol. 22, No. 17, 2001, p. 2325-2331.

Research output: Contribution to journalArticle

Affatato, S. ; Fernandes, B. ; Tucci, A. ; Esposito, L. ; Toni, A. / Isolation and morphological characterisation of UHMWPE wear debris generated in vitro. In: Biomaterials. 2001 ; Vol. 22, No. 17. pp. 2325-2331.
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