Isolation and partial purification of hepatic stimulatory substance

A. Francavilla, P. Ove, L. Polimeno, M. Coetzee, L. Makowka, M. Barone, D. H. Van Thiel, T. E. Starzl

Research output: Contribution to journalArticle

Abstract

The purpose of this study was to purify and characterize hepatic stimulatory substance (HSS), a protein found in the liver that has been reported to stimulate hepatic DNA synthesis and hepatocyte replication. HSS has been partially purified by successive steps, involving ethanol precipitation, ultrafiltration, and fast protein lipid chromatography (FPLC). The activity of this factor has been tested in 40% hepatectomized rats.

Original languageEnglish
Pages (from-to)719-721
Number of pages3
JournalTransplantation Proceedings
Volume20
Issue number1 SUPPL. 1
Publication statusPublished - 1988

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Liver
Ultrafiltration
Chromatography
Hepatocytes
Proteins
Ethanol
Lipids
DNA

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Francavilla, A., Ove, P., Polimeno, L., Coetzee, M., Makowka, L., Barone, M., ... Starzl, T. E. (1988). Isolation and partial purification of hepatic stimulatory substance. Transplantation Proceedings, 20(1 SUPPL. 1), 719-721.

Isolation and partial purification of hepatic stimulatory substance. / Francavilla, A.; Ove, P.; Polimeno, L.; Coetzee, M.; Makowka, L.; Barone, M.; Van Thiel, D. H.; Starzl, T. E.

In: Transplantation Proceedings, Vol. 20, No. 1 SUPPL. 1, 1988, p. 719-721.

Research output: Contribution to journalArticle

Francavilla, A, Ove, P, Polimeno, L, Coetzee, M, Makowka, L, Barone, M, Van Thiel, DH & Starzl, TE 1988, 'Isolation and partial purification of hepatic stimulatory substance', Transplantation Proceedings, vol. 20, no. 1 SUPPL. 1, pp. 719-721.
Francavilla A, Ove P, Polimeno L, Coetzee M, Makowka L, Barone M et al. Isolation and partial purification of hepatic stimulatory substance. Transplantation Proceedings. 1988;20(1 SUPPL. 1):719-721.
Francavilla, A. ; Ove, P. ; Polimeno, L. ; Coetzee, M. ; Makowka, L. ; Barone, M. ; Van Thiel, D. H. ; Starzl, T. E. / Isolation and partial purification of hepatic stimulatory substance. In: Transplantation Proceedings. 1988 ; Vol. 20, No. 1 SUPPL. 1. pp. 719-721.
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