Isolation of infectious zika virus from saliva and prolonged viral RNA shedding in a traveller returning from the dominican republic to Italy, January 2016

Luisa Barzon, M. Pacenti, A. Berto, A. Sinigaglia, E. Franchin, E. Lavezzo, P. Brugnaro, G. Palù

Research output: Contribution to journalArticle


We report the isolation of infectious Zika virus (ZIKV) in cell culture from the saliva of a patient who developed a febrile illness after returning from the Dominican Republic to Italy, in January 2016. The patient had prolonged shedding of viral RNA in saliva and urine, at higher load than in blood, for up to 29 days after symptom onset. Sequencing of ZIKV genome showed relatedness with strains from Latin America.

Original languageEnglish
JournalEuro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin
Issue number10
Publication statusPublished - Mar 10 2016


ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health
  • Virology

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