Isolation of KPC 3-producing Enterobacter aerogenes in a patient colonized by MDR Klebsiella pneumoniae

Carolina Venditti; Laura Villa; Alessandro Capone; Daniela Fortini; Silvia D'Arezzo; Carla Nisii; Eugenio Bordi; Vincenzo Puro; Mario Antonini; Alessandra Carattoli; Maria Adriana Cataldo; Nicola Petrosillo; Antonino Di Caro

Isolation of KPC 3-producing Enterobacter aerogenes in a patient colonized by MDR Klebsiella pneumoniae

Carolina Venditti, Laura Villa, Alessandro Capone, Daniela Fortini, Silvia D'Arezzo, Carla Nisii, Eugenio Bordi, Vincenzo Puro, Mario Antonini, Alessandra Carattoli, Maria Adriana Cataldo, Nicola Petrosillo, Antonino Di Caro

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani

Research output: Contribution to journal › Article › peer-review

Abstract

We describe the interspecies transmission of the plasmid-mediated bla_KPC-3 gene, which confers carbapenem resistance, between clinically relevant gram-negative bacteria in a single patient. A KPC-3 producing Enterobacter aerogenes was isolated from a hospitalized patient previously colonized and then infected by a Klebsiella pneumoniae ST101 carrying the blaKPC-3 gene. The strains showed identical plasmids. Since intense horizontal exchanges among bacteria can occur in the gut, clinicians should be aware that patients colonized by carbapenem-resistant K. pneumoniae could become carriers of other carbapenem-resistant Enterobacteriaceae.

Original language	English
Pages (from-to)	310-313
Number of pages	4
Journal	New Microbiologica
Volume	39
Issue number	4
Publication status	Published - Oct 1 2016

Keywords

Galactomannan antigen
Magnusiomyces capitatus
Maldi-tof identification
Pleural infection
Posaconazole

ASJC Scopus subject areas

Microbiology (medical)

Cite this

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title = "Isolation of KPC 3-producing Enterobacter aerogenes in a patient colonized by MDR Klebsiella pneumoniae",

abstract = "We describe the interspecies transmission of the plasmid-mediated blaKPC-3 gene, which confers carbapenem resistance, between clinically relevant gram-negative bacteria in a single patient. A KPC-3 producing Enterobacter aerogenes was isolated from a hospitalized patient previously colonized and then infected by a Klebsiella pneumoniae ST101 carrying the blaKPC-3 gene. The strains showed identical plasmids. Since intense horizontal exchanges among bacteria can occur in the gut, clinicians should be aware that patients colonized by carbapenem-resistant K. pneumoniae could become carriers of other carbapenem-resistant Enterobacteriaceae.",

keywords = "Galactomannan antigen, Magnusiomyces capitatus, Maldi-tof identification, Pleural infection, Posaconazole",

author = "Carolina Venditti and Laura Villa and Alessandro Capone and Daniela Fortini and Silvia D'Arezzo and Carla Nisii and Eugenio Bordi and Vincenzo Puro and Mario Antonini and Alessandra Carattoli and Cataldo, {Maria Adriana} and Nicola Petrosillo and {Di Caro}, Antonino",

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T1 - Isolation of KPC 3-producing Enterobacter aerogenes in a patient colonized by MDR Klebsiella pneumoniae

AU - Venditti, Carolina

AU - Villa, Laura

AU - Capone, Alessandro

AU - Fortini, Daniela

AU - D'Arezzo, Silvia

AU - Nisii, Carla

AU - Bordi, Eugenio

AU - Puro, Vincenzo

AU - Antonini, Mario

AU - Carattoli, Alessandra

AU - Cataldo, Maria Adriana

AU - Petrosillo, Nicola

AU - Di Caro, Antonino

PY - 2016/10/1

Y1 - 2016/10/1

N2 - We describe the interspecies transmission of the plasmid-mediated blaKPC-3 gene, which confers carbapenem resistance, between clinically relevant gram-negative bacteria in a single patient. A KPC-3 producing Enterobacter aerogenes was isolated from a hospitalized patient previously colonized and then infected by a Klebsiella pneumoniae ST101 carrying the blaKPC-3 gene. The strains showed identical plasmids. Since intense horizontal exchanges among bacteria can occur in the gut, clinicians should be aware that patients colonized by carbapenem-resistant K. pneumoniae could become carriers of other carbapenem-resistant Enterobacteriaceae.

AB - We describe the interspecies transmission of the plasmid-mediated blaKPC-3 gene, which confers carbapenem resistance, between clinically relevant gram-negative bacteria in a single patient. A KPC-3 producing Enterobacter aerogenes was isolated from a hospitalized patient previously colonized and then infected by a Klebsiella pneumoniae ST101 carrying the blaKPC-3 gene. The strains showed identical plasmids. Since intense horizontal exchanges among bacteria can occur in the gut, clinicians should be aware that patients colonized by carbapenem-resistant K. pneumoniae could become carriers of other carbapenem-resistant Enterobacteriaceae.

KW - Galactomannan antigen

KW - Magnusiomyces capitatus

KW - Maldi-tof identification

KW - Pleural infection

KW - Posaconazole

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VL - 39

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JF - New Microbiologica

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IS - 4

ER -

Isolation of KPC 3-producing Enterobacter aerogenes in a patient colonized by MDR Klebsiella pneumoniae

Abstract

Keywords

ASJC Scopus subject areas

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