Isolation of Staphylococcus aureus and progression of periodontal lesions in aggressive periodontitis

Claudio Passariello, A. Lucchese, A. Virga, F. Pera, P. Gigola

Research output: Contribution to journalArticle

Abstract

This work evaluates whether isolation and toxicity of subgingival Staphylococcus aureus strains correlate with progression of periodontal lesions and whether isolates are characterized by a specific genomic background. The study involved 165 subjects affected by generalized aggressive periodontitis. Three sets of samples of supragingival and subgingival plaque were obtained at 45-day intervals from active and non-active sites, to detect S. aureus. Susceptibility to antibiotics, the presence of 17 genes, genomic restriction profiles and multilocus sequence typing (MLST) were performed to characterize all isolates. S. aureus was detected in 37.6% of the subjects. Subgingival colonization rates were 66.1% and 12.9% for active and non-active sites, respectively (P

Original languageEnglish
Pages (from-to)501-513
Number of pages13
JournalEuropean Journal of Inflammation
Volume10
Issue number3
Publication statusPublished - Sep 2012

Keywords

  • Aggressive periodontitis
  • Staphylococcus aureus
  • Virulence factors

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

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