Translated title of the contribution: Isotretinoin. Osseous and ligamentous alterations

C. Capobianco, V. Bettoli, U. Albisinni, L. Merlini, C. Vincenzi

Research output: Contribution to journalArticlepeer-review


Thirty patients, affected by nodulo-cystic acne, were treated with isotretinoin for 3-7 months, at the average dosage of 0,5-0,7 mg/kg/day. These patients were studied in order to evaluate the prevalence of ossifications and/or calcifications of the spine. X-rays of the lumbar and cervical segment of the spine were performed 1-26 months after stopping therapy. In 17 out of 30 patients X-rays were also performed before treatment. No pathological alterations, either vertebral or ligamentous, were evident.

Translated title of the contributionIsotretinoin. Osseous and ligamentous alterations
Original languageItalian
Pages (from-to)291-293
Number of pages3
JournalGiornale Italiano di Dermatologia e Venereologia
Issue number6
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Dermatology

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