Italian Association of Clinical Endocrinologists (AME) & Italian Association of Clinical Diabetologists (AMD) Position Statement: Diabetes mellitus and thyroid disorders: recommendations for clinical practice

Edoardo Guastamacchia, Vincenzo Triggiani, Alberto Aglialoro, Antimo Aiello, Lucia Ianni, Mauro Maccario, Michele Zini, Carlo Giorda, Rinaldo Guglielmi, Corrado Betterle, Roberto Attanasio, Giorgio Borretta, Piernicola Garofalo, Enrico Papini, Roberto Castello, Antonio Ceriello

Research output: Contribution to journalArticle

Abstract

Thyroid disease and diabetes mellitus, the most common disorders in endocrine practice, are not infrequently associated in the same subject. An altered thyroid function may affect glucose tolerance and worsen metabolic control in patients with diabetes. Thyrotoxicosis increases the risk of hyperglycemic emergencies, while a clinically relevant hypothyroidism may have a detrimental effect on glycemic control in diabetic patients. The association of alterations in thyroid function with diabetes mellitus may adversely affect the risk of cardiovascular and microvascular complications resulting from diabetes. Moreover, the treatments used for both diabetes and thyroid disease, respectively, can impact one other. Finally, multinodular goiter, but not thyroid carcinoma, was shown to be more prevalent in type 2 diabetes mellitus. Aim of the present Position Statement is to focus on the evidence concerning the association of thyroid disease and diabetes mellitus and to provide some practical suggestions for an updated clinical management.

Original languageEnglish
Pages (from-to)339-352
Number of pages14
JournalEndocrine
Volume49
Issue number2
DOIs
Publication statusPublished - Nov 18 2015

Keywords

  • Autoimmune thyroid diseases
  • Diabetes mellitus
  • Glycemic control
  • Hyperthyroidism
  • Hypothyroidism
  • Thyroid disorders

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

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    Guastamacchia, E., Triggiani, V., Aglialoro, A., Aiello, A., Ianni, L., Maccario, M., Zini, M., Giorda, C., Guglielmi, R., Betterle, C., Attanasio, R., Borretta, G., Garofalo, P., Papini, E., Castello, R., & Ceriello, A. (2015). Italian Association of Clinical Endocrinologists (AME) & Italian Association of Clinical Diabetologists (AMD) Position Statement: Diabetes mellitus and thyroid disorders: recommendations for clinical practice. Endocrine, 49(2), 339-352. https://doi.org/10.1007/s12020-014-0474-9