Italian consensus conference for the outpatient autologous stem cell transplantation management in multiple myeloma

Massimo Martino, Roberto Massimo Lemoli, Corrado Girmenia, Luca Castagna, B. Bruno, Federica Cavallo, Massimo Offidani, Ilaria Scortechini, Mauro Montanari, G. Milone, Laura Postacchini, Attilio Olivieri

Research output: Contribution to journalArticle

Abstract

Multiple myeloma (MM) is the leading indication for autologous stem cell transplantation (ASCT) worldwide. The safety and efficacy of reducing hospital stay for MM patients undergoing ASCT have been widely explored, and different outpatient models have been proposed. However, there is no agreement on the criteria for selecting patients eligible for this strategy as well as the standards for their clinical management. On the basis of this rationale, the Italian Group for Stem Cell Transplantation (GITMO) endorsed a project to develop guidelines for the management of outpatient ASCT in MM, using evidence-based knowledge and consensus-formation techniques. An expert panel convened to discuss the currently available data on the practice of outpatient ASCT management and formulated recommendations according to the supporting evidence. Evidence gaps were filled with consensus-based statements. Three main topics were addressed: (1) the identification of criteria for selecting MM patients eligible for outpatient ASCT management; (2) the definition of standard procedures for performing outpatient ASCT (model, supportive care and monitoring during the aplastic phase); (3) the definition of the standard criteria and procedures for re-hospitalization during the aplastic phase at home. Herein, we report the summary and the results of the discussion and the consensus.Bone Marrow Transplantation advance online publication, 4 April 2016; doi:10.1038/bmt.2016.79.

Original languageEnglish
JournalBone Marrow Transplantation
DOIs
Publication statusAccepted/In press - Apr 4 2016

ASJC Scopus subject areas

  • Hematology
  • Transplantation

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    Martino, M., Lemoli, R. M., Girmenia, C., Castagna, L., Bruno, B., Cavallo, F., Offidani, M., Scortechini, I., Montanari, M., Milone, G., Postacchini, L., & Olivieri, A. (Accepted/In press). Italian consensus conference for the outpatient autologous stem cell transplantation management in multiple myeloma. Bone Marrow Transplantation. https://doi.org/10.1038/bmt.2016.79