Italian consensus on diagnosis and treatment of differentiated thyroid cancer: joint statements of six Italian societies

F. Pacini, F. Basolo, R. Bellantone, G. Boni, M.A. Cannizzaro, M. De Palma, C. Durante, R. Elisei, G. Fadda, A. Frasoldati, L. Fugazzola, R. Guglielmi, C.P. Lombardi, P. Miccoli, E. Papini, G. Pellegriti, L. Pezzullo, A. Pontecorvi, M. Salvatori, E. SeregniP. Vitti

Research output: Contribution to journalArticlepeer-review


Background: Thyroid nodules are a common clinical problem, and differentiated thyroid cancer is becoming increasingly prevalent. Methods: Six scientific Italian societies entitled to cure thyroid cancer patients (the Italian Thyroid Association, the Medical Endocrinology Association, the Italian Society of Endocrinology, the Italian Association of Nuclear Medicine and Molecular Imaging, the Italian Society of Unified Endocrine Surgery and the Italian Society of Anatomic Pathology and Diagnostic Cytology) felt the need to develop a consensus report based on significant scientific advances occurred in the field. Objective: The document includes recommendations regarding initial evaluation of thyroid nodules, clinical and ultrasound criteria for fine-needle aspiration biopsy, initial management of thyroid cancer including staging and risk assessment, surgical management, radioiodine remnant ablation, and levothyroxine therapy, short-term and long-term follow-up strategies, and management of recurrent and metastatic disease. The objective of this consensus is to inform clinicians, patients, researchers, and health policy makers about the best strategies (and their limitations) relating to the diagnosis and treatment of differentiated thyroid cancer. © 2018, Italian Society of Endocrinology (SIE).
Original languageEnglish
Pages (from-to)849-876
Number of pages28
JournalJournal of Endocrinological Investigation
Issue number7
Publication statusPublished - 2018


  • iodine 131
  • lenvatinib
  • levothyroxine
  • radioactive iodine
  • sorafenib, Article
  • cancer diagnosis
  • cancer patient
  • cancer recurrence
  • cancer staging
  • cancer therapy
  • clinical feature
  • consensus
  • differentiated thyroid cancer
  • echography
  • fine needle aspiration biopsy
  • follow up
  • human
  • Italy
  • medical society
  • metastasis
  • practice guideline
  • risk assessment
  • thyroid nodule
  • adenocarcinoma
  • endocrinology
  • molecular imaging
  • nuclear medicine
  • organization and management
  • procedures
  • scintiscanning
  • standards
  • thyroid tumor, Adenocarcinoma
  • Biopsy, Fine-Needle
  • Consensus
  • Endocrinology
  • Humans
  • Molecular Imaging
  • Nuclear Medicine
  • Radionuclide Imaging
  • Societies, Medical
  • Thyroid Neoplasms
  • Ultrasonography


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