Italian guidelines in pemphigus - adapted from the European Dermatology Forum (EDF) and European Academy of Dermatology and Venerology (EADV)

Claudio Feliciani, Emanuele Cozzani, Angelo V. Marzano, Marzia Caproni, Giovanni Di Zenzo, Piergiacomo Calzavara-Pinton

Research output: Contribution to journalReview article

Abstract

Pemphigus is a life threatening autoimmune epidermal blistering disease involving skin and mucous membranes. Pemphigus usually affects middle age men and women involving oral mucosa first and then spreading on the skin. It is caused by the presence of autoantibodies (IgG and less frequently by IgA) directed against desmogleins, and/or other glycoproteins that plays a critical role in cell-cell attachment. Upon a predisposing genetic background, different agents have been shown to act as triggers for the pathogenesis of pemphigus. This guideline for the diagnosis and treatment of pemphigus has been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Dermatology Forum in collaboration with the European Academy of Dermatology and Venereology. It summarizes evidence-based and expert-based recommendations (S2 level).

Original languageEnglish
Pages (from-to)599-608
Number of pages10
JournalGiornale Italiano di Dermatologia e Venereologia
Volume153
Issue number5
DOIs
Publication statusPublished - Oct 1 2018

Keywords

  • Pemphigus - Guidelines - Skin diseases
  • Vesiculobullous

ASJC Scopus subject areas

  • Dermatology

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