TY - JOUR
T1 - Italian multicentre study of peroneal mononeuropathy
T2 - Multiperspective follow-up
AU - Aprile, I.
AU - Tonali, P.
AU - Caliandro, P.
AU - Pazzaglia, C.
AU - Foschini, M.
AU - Di Stasio, E.
AU - Mondelli, M.
AU - Padua, L.
PY - 2009
Y1 - 2009
N2 - The main objective of this study is to assess the course of peroneal mononeuropathy (PM). The study design includes Clinical and Prospective study. The setting involves neurophysiological Service. From November 2002 to January 2004, we enroled 69 consecutive patients and prospectively followed up 49 patients with multiple measurements. Comparison was made between follow-up and baseline values, and baseline factors were used to predict the PM evolution in multiple regression analysis. At follow-up, we observed a significant improvement of all clinical, neurophysiological and disability measurements, and physical aspects of quality of life (QoL). Greater muscle strength of tibialis anterior and higher conduction velocity of peroneal nerve at baseline were seen to be positive prognostic factors. A better evolution of mental aspects of QoL was observed in the subacute group and in younger patients, while a better physical evolution in QoL was observed in women. Rehabilitation is ambiguously associated with a better Deambulation Index but lower ratings in mental aspects of QoL. In conclusion, PM shows a positive spontaneous course and rehabilitation seems to help the recovery of deambulation. Further studies on the effects of conventional rehabilitation are needed.
AB - The main objective of this study is to assess the course of peroneal mononeuropathy (PM). The study design includes Clinical and Prospective study. The setting involves neurophysiological Service. From November 2002 to January 2004, we enroled 69 consecutive patients and prospectively followed up 49 patients with multiple measurements. Comparison was made between follow-up and baseline values, and baseline factors were used to predict the PM evolution in multiple regression analysis. At follow-up, we observed a significant improvement of all clinical, neurophysiological and disability measurements, and physical aspects of quality of life (QoL). Greater muscle strength of tibialis anterior and higher conduction velocity of peroneal nerve at baseline were seen to be positive prognostic factors. A better evolution of mental aspects of QoL was observed in the subacute group and in younger patients, while a better physical evolution in QoL was observed in women. Rehabilitation is ambiguously associated with a better Deambulation Index but lower ratings in mental aspects of QoL. In conclusion, PM shows a positive spontaneous course and rehabilitation seems to help the recovery of deambulation. Further studies on the effects of conventional rehabilitation are needed.
KW - Follow-up
KW - Multicentre
KW - Natural history
KW - Outcome
KW - Peroneal mononeuropathy
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U2 - 10.1007/s10072-009-0010-5
DO - 10.1007/s10072-009-0010-5
M3 - Article
C2 - 19153647
AN - SCOPUS:60449116528
VL - 30
SP - 37
EP - 44
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - 1
ER -