Studio Italiano sulla Depressione in Medicina Generale (Italian Study on Depression - ISD)

Translated title of the contribution: Italian Study on Depression (ISD) in general practice

Guido Danti, Francesco Del Zotti, Maurizio Bonati, Maria Font, Mauro Miselli, Marilena Romero, Gianni Tognoni, Clara Pietraru, Alvise Spolaor, Loretta Castellani, Roberta Joppi, Luigi Mezzalira, Marta Baviera, Chiara Roni, Caterina Anecchino, Katiuscia Di Biagio, Elisa Sasso

Research output: Contribution to journalArticlepeer-review


Depressive disorders are a major health problem in primary care: nine out of 10 depressed patients are reported to be managed directly by their general practitioner. Nevertheless, most available data on the yield of diagnostic criteria and of treatment efficacy were developed and applied in psychiatric settings and cannot be considered as terms of reference for the care conditions which characterize general practice. The Italian Society of Clinical Pharmacy (SIFO) in collaboration with the Societies of General Practice, the International Society of Drug Bulletins and Local Health Units, is promoting the Italian Study on Depression in general practice (ISD). The aims of this study are: • to describe the epidemiology of the overall spectrum of depressive disorders in general practice, using broader diagnostic approach which foresees for inclusion also informal criteria (e.g. descriptive symptoms and/or perception of depressive conditions); • to evaluate comparatively outcomes of different management and treatment strategies commonly used and/or practicable in primary care. The protocol design is articulated as a prospective observational outcome cohort, with a nested randomized trial of those patients for whom the treatment decisions are uncertain. A broad network of 200 - 250 GPs is expected to include into the study up to 2,000 patients, to be followed up for at least 12 months.

Translated title of the contributionItalian Study on Depression (ISD) in general practice
Original languageItalian
Pages (from-to)42-54
Number of pages13
JournalGiornale Italiano di Farmacia Clinica
Issue number1
Publication statusPublished - Jan 2007

ASJC Scopus subject areas

  • Pharmacology (medical)


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