IVF

Induction of ovulation in poor responders

P. G. Crosignani, G. Ragni, G. C. Lombroso, C. Scarduelli, L. de Lauretis, A. Caccamo, L. Dalprà, V. Cavioni, C. Cristiani, H. Wyssling, M. D. Olivares

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

All IVF programs have a consistent rate of failure in inducing ovulations. Pharmacological induction of ovulation is otherwise crucial for an IVF program because of the need for more than one ovum. Since it is well known that the best candidates for HMG treatment are hypogonadotropic women a short reversible hypogonadotropic state was induced in IVF patients by LH-RH agonist (Buserelin). Superovulation was then achieved with very high initial doses of FSH (Metrodin) in order to maximize the ovarian response. This technique used in 116 IVF women induced a satisfactory follicle growth even in 70% of the patients already poorly responsive to HMG stimulation.

Original languageEnglish
Pages (from-to)171-173
Number of pages3
JournalJournal of Steroid Biochemistry
Volume32
Issue number1 PART 2
DOIs
Publication statusPublished - 1989

Fingerprint

Urofollitropin
Buserelin
Ovulation Induction
Gonadotropin-Releasing Hormone
Superovulation
Ovulation
Ovum
Pharmacology
Growth
Therapeutics

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

Cite this

Crosignani, P. G., Ragni, G., Lombroso, G. C., Scarduelli, C., de Lauretis, L., Caccamo, A., ... Olivares, M. D. (1989). IVF: Induction of ovulation in poor responders. Journal of Steroid Biochemistry, 32(1 PART 2), 171-173. https://doi.org/10.1016/0022-4731(89)90160-X

IVF : Induction of ovulation in poor responders. / Crosignani, P. G.; Ragni, G.; Lombroso, G. C.; Scarduelli, C.; de Lauretis, L.; Caccamo, A.; Dalprà, L.; Cavioni, V.; Cristiani, C.; Wyssling, H.; Olivares, M. D.

In: Journal of Steroid Biochemistry, Vol. 32, No. 1 PART 2, 1989, p. 171-173.

Research output: Contribution to journalArticle

Crosignani, PG, Ragni, G, Lombroso, GC, Scarduelli, C, de Lauretis, L, Caccamo, A, Dalprà, L, Cavioni, V, Cristiani, C, Wyssling, H & Olivares, MD 1989, 'IVF: Induction of ovulation in poor responders', Journal of Steroid Biochemistry, vol. 32, no. 1 PART 2, pp. 171-173. https://doi.org/10.1016/0022-4731(89)90160-X
Crosignani PG, Ragni G, Lombroso GC, Scarduelli C, de Lauretis L, Caccamo A et al. IVF: Induction of ovulation in poor responders. Journal of Steroid Biochemistry. 1989;32(1 PART 2):171-173. https://doi.org/10.1016/0022-4731(89)90160-X
Crosignani, P. G. ; Ragni, G. ; Lombroso, G. C. ; Scarduelli, C. ; de Lauretis, L. ; Caccamo, A. ; Dalprà, L. ; Cavioni, V. ; Cristiani, C. ; Wyssling, H. ; Olivares, M. D. / IVF : Induction of ovulation in poor responders. In: Journal of Steroid Biochemistry. 1989 ; Vol. 32, No. 1 PART 2. pp. 171-173.
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