Job satisfaction among physicians and nurses involved in the management of multiple sclerosis: the role of happiness and meaning at work

Luca Negri, Sabina Cilia, Monica Falautano, Monica Grobberio, Claudia Niccolai, Marianna Pattini, Erika Pietrolongo, Maria Esmeralda Quartuccio, Rosa Gemma Viterbo, Beatrice Allegri, Maria Pia Amato, Miriam Benin, Giovanna De Luca, Claudio Gasperini, Eleonora Minacapelli, Francesco Patti, Maria Trojano, Marta Bassi

Research output: Contribution to journalArticlepeer-review


Objective: Health professionals caring for persons with multiple sclerosis (MS) are faced with increasingly complex working conditions that can undermine their job satisfaction and the quality of their healthcare services. The aim of this study was to delve into health professionals’ job satisfaction by assessing the predictive role of happiness and meaning at work. Specifically, it was hypothesized that job meaning would moderate the relationship between job happiness and satisfaction. Methods: The study hypothesis was tested among 108 healthcare professionals (53 physicians and 55 nurses) working in eight MS centers in Italy. Participants were administered the Eudaimonic and Hedonic Happiness Investigation and the Job Satisfaction Questionnaire. Hierarchical regression analysis was performed to test the moderating role of job meaning between job happiness and satisfaction. Results: A significant interaction effect of job happiness and meaning on job satisfaction was identified for both physicians and nurses. When work was attributed low meaning, participants experiencing high job happiness were more satisfied with their work than those reporting low happiness; by contrast, when work was perceived as highly meaningful, participants’ levels of job happiness did not significantly contribute to job satisfaction. Conclusions: Focusing on the interplay between job happiness and meaning, findings bring forward practical suggestions for the preservation and promotion of job satisfaction among health professionals working with MS patients. Particularly, they suggest the need to strengthen those job-related aspects that may enhance job meaning, thus providing health professionals with significant reasons to persevere in their work in the face of daily challenges.

Original languageEnglish
JournalNeurological Sciences
Publication statusPublished - Aug 2021


  • Healthcare professionals
  • Job happiness
  • Job meaning
  • Job satisfaction
  • Multiple sclerosis

ASJC Scopus subject areas

  • Dermatology
  • Clinical Neurology
  • Psychiatry and Mental health


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