Joint practice guidelines for radionuclide lymphoscintigraphy for sentinel node localization in oral/oropharyngeal squamous cell carcinoma

L. W T Alkureishi, Z. Burak, J. A. Alvarez, J. Ballinger, A. Bilde, A. J. Britten, L. Calabrese, C. Chiesa, A. Chiti, R. De Bree, H. W. Gray, K. Hunter, A. F. Kovacs, M. Lassmann, C. R. Leemans, G. Mamelle, M. McGurk, J. Mortensen, T. Poli, T. ShoaibP. Sloan, J. A. Sorensen, S. J. Stoeckli, J. B. Thomsen, G. Trifiro, J. Werner, G. L. Ross

Research output: Contribution to journalArticle

Abstract

Involvement of the cervical lymph nodes is the most important prognostic factor for patients with oral/oropharyngeal squamous cell carcinoma (OSCC), and the decision of whether to electively treat patients with clinically negative necks remains a controversial topic. Sentinel node biopsy (SNB) provides a minimally invasive method for determining the disease status of the cervical node basin, without the need for a formal neck dissection. This technique potentially improves the accuracy of histologic nodal staging and avoids overtreating three-quarters of this patient population, minimizing associated morbidity. The technique has been validated for patients with OSCC, and larger-scale studies are in progress to determine its exact role in the management of this patient population. This document is designed to outline the current best practice guidelines for the provision of SNB in patients with early-stage OSCC, and to provide a framework for the currently evolving recommendations for its use. Preparation of this guideline was carried out by a multidisciplinary surgical/nuclear medicine/pathology expert panel under the joint auspices of the European Association of Nuclear Medicine (EANM) Oncology Committee and the Sentinel European Node Trial (SENT) Committee.

Original languageEnglish
Pages (from-to)3190-3210
Number of pages21
JournalAnnals of Surgical Oncology
Volume16
Issue number11
DOIs
Publication statusPublished - Nov 2009

Keywords

  • Carcinomas, squamous cell
  • Head and neck neoplasms
  • Radionuclide imaging
  • Sentinel lymph node biopsy
  • Technetium Tc-99m human serum albumin colloid

ASJC Scopus subject areas

  • Surgery
  • Oncology

Fingerprint Dive into the research topics of 'Joint practice guidelines for radionuclide lymphoscintigraphy for sentinel node localization in oral/oropharyngeal squamous cell carcinoma'. Together they form a unique fingerprint.

  • Cite this

    Alkureishi, L. W. T., Burak, Z., Alvarez, J. A., Ballinger, J., Bilde, A., Britten, A. J., Calabrese, L., Chiesa, C., Chiti, A., De Bree, R., Gray, H. W., Hunter, K., Kovacs, A. F., Lassmann, M., Leemans, C. R., Mamelle, G., McGurk, M., Mortensen, J., Poli, T., ... Ross, G. L. (2009). Joint practice guidelines for radionuclide lymphoscintigraphy for sentinel node localization in oral/oropharyngeal squamous cell carcinoma. Annals of Surgical Oncology, 16(11), 3190-3210. https://doi.org/10.1245/s10434-009-0726-8