Junctional pattern in the squamous metaplasia of the female trigone. A freeze-fracture study

M. Sideri, G. de Virgiliis, R. Rainoldi, A. Ferrari, G. Remotti

Research output: Contribution to journalArticlepeer-review

Abstract

The junctional pattern of squamous metaplasia in the female trigone was studied by the freeze-fracture technique. Desmosomes were observed in all epithelial layers and varied in complexity from the basal to the superficial layers. Gap junctions were observed in the lower and upper epithelial layers. Tight junctions were detected occasionally in the superficial layer only, which appeared as maculae and did not form zonulae occludens. These data support previous suggestions that the squamous metaplastic epithelium is not waterproof and may interfere with the contraction-expansion mechanism of the bladder.

Original languageEnglish
Pages (from-to)280-283
Number of pages4
JournalJournal of Urology
Volume129
Issue number2
Publication statusPublished - 1983

ASJC Scopus subject areas

  • Urology

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