Juvenile eosinophilic fasciitis: Three case reports with a review of the literature

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective. Eosinophilic fasciitis is an uncommon scleroderma-like disorder characterised by induration and thickening of skin and soft tissue, usually associated with peripheral eosinophilia, poorly characterised in childhood. Methods. We report 3 paediatric cases of eosinophilic fasciitis showing unusual clinical and histopathological features with a review of the literature. Results. All cases presented progressive motility impairment started from upper limbs with no skin abnormalities. All cases showed systemic inflammatory involvement and 2 patients had acute complications. Two patients developed disabling outcomes despite appropriate treatments. Conclusion. Eosinophilic fasciitis may present unusual clinical and histopathological features during childhood and requires early recognition in order to prevent acute complications and disabling outcomes.

Original languageEnglish
Pages (from-to)527-530
Number of pages4
JournalClinical and Experimental Rheumatology
Volume34
Issue number3
Publication statusPublished - 2016

Fingerprint

Skin Abnormalities
Eosinophilia
Upper Extremity
Pediatrics
Skin
Eosinophilic Fasciitis
Therapeutics

Keywords

  • Eosinophilia
  • Juvenile-onset scleroderma
  • Paediatrics
  • Rheumatology

ASJC Scopus subject areas

  • Medicine(all)

Cite this

@article{cb4469f22eda4765b164dcd1dbcd2d77,
title = "Juvenile eosinophilic fasciitis: Three case reports with a review of the literature",
abstract = "Objective. Eosinophilic fasciitis is an uncommon scleroderma-like disorder characterised by induration and thickening of skin and soft tissue, usually associated with peripheral eosinophilia, poorly characterised in childhood. Methods. We report 3 paediatric cases of eosinophilic fasciitis showing unusual clinical and histopathological features with a review of the literature. Results. All cases presented progressive motility impairment started from upper limbs with no skin abnormalities. All cases showed systemic inflammatory involvement and 2 patients had acute complications. Two patients developed disabling outcomes despite appropriate treatments. Conclusion. Eosinophilic fasciitis may present unusual clinical and histopathological features during childhood and requires early recognition in order to prevent acute complications and disabling outcomes.",
keywords = "Eosinophilia, Juvenile-onset scleroderma, Paediatrics, Rheumatology",
author = "Riccardo Papa and Paolo Nozza and Claudio Granata and Roberta Caorsi and Marco Gattorno and Alberto Martini and Paolo Picco",
year = "2016",
language = "English",
volume = "34",
pages = "527--530",
journal = "Clinical and Experimental Rheumatology",
issn = "0392-856X",
publisher = "Clinical and Experimental Rheumatology S.A.S.",
number = "3",

}

TY - JOUR

T1 - Juvenile eosinophilic fasciitis

T2 - Three case reports with a review of the literature

AU - Papa, Riccardo

AU - Nozza, Paolo

AU - Granata, Claudio

AU - Caorsi, Roberta

AU - Gattorno, Marco

AU - Martini, Alberto

AU - Picco, Paolo

PY - 2016

Y1 - 2016

N2 - Objective. Eosinophilic fasciitis is an uncommon scleroderma-like disorder characterised by induration and thickening of skin and soft tissue, usually associated with peripheral eosinophilia, poorly characterised in childhood. Methods. We report 3 paediatric cases of eosinophilic fasciitis showing unusual clinical and histopathological features with a review of the literature. Results. All cases presented progressive motility impairment started from upper limbs with no skin abnormalities. All cases showed systemic inflammatory involvement and 2 patients had acute complications. Two patients developed disabling outcomes despite appropriate treatments. Conclusion. Eosinophilic fasciitis may present unusual clinical and histopathological features during childhood and requires early recognition in order to prevent acute complications and disabling outcomes.

AB - Objective. Eosinophilic fasciitis is an uncommon scleroderma-like disorder characterised by induration and thickening of skin and soft tissue, usually associated with peripheral eosinophilia, poorly characterised in childhood. Methods. We report 3 paediatric cases of eosinophilic fasciitis showing unusual clinical and histopathological features with a review of the literature. Results. All cases presented progressive motility impairment started from upper limbs with no skin abnormalities. All cases showed systemic inflammatory involvement and 2 patients had acute complications. Two patients developed disabling outcomes despite appropriate treatments. Conclusion. Eosinophilic fasciitis may present unusual clinical and histopathological features during childhood and requires early recognition in order to prevent acute complications and disabling outcomes.

KW - Eosinophilia

KW - Juvenile-onset scleroderma

KW - Paediatrics

KW - Rheumatology

UR - http://www.scopus.com/inward/record.url?scp=84982862087&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84982862087&partnerID=8YFLogxK

M3 - Article

C2 - 27268780

AN - SCOPUS:84982862087

VL - 34

SP - 527

EP - 530

JO - Clinical and Experimental Rheumatology

JF - Clinical and Experimental Rheumatology

SN - 0392-856X

IS - 3

ER -