Juvenile psoriatic arthritis and acquired sensorineural hearing loss in a teenager: Is there an association?

Teresa Giani, Gabriele Simonini, Claudio Lunardi, Antonio Puccetti, Maurizio De Martino, Fernanda Falcini

Research output: Contribution to journalArticlepeer-review

Abstract

Autoimmune inner ear disease is a cause of sensorineural hearing loss, first described in 1979 by McCabe. The occurrence during rheumatic diseases is already documented in adults, but to our knowledge, this evidence is still lacking in children. A 13-yr-old girl affected by juvenile psoriatic arthritis, treated with etanercept, developed a bilateral and asymmetric sensorineural deafness. The patient significantly improved after steroid administration. Once ruled out the principal causes of sensorineural hearing loss, we also considered the hypothesis of an anti-TNF side effect. However, the clinical presentation, the efficacy on steroid treatment and the presence of inner ear auto-antibodies prompt us to consider autoimmune-SNHL as the most plausible diagnosis. The young age of our patient seems to suggest a genetic susceptibility to autoimmunity and supports the concept of associated autoimmune diseases.

Original languageEnglish
Pages (from-to)344-346
Number of pages3
JournalClinical and Experimental Rheumatology
Volume24
Issue number3
Publication statusPublished - May 2006

Keywords

  • Etanercept
  • Juvenile psoriatic arthritis
  • Sensorineural hearing loss

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

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