Abstract
ABVI: Two groups of young adults with juvenile stroke (JS) or migraine with aura (MA) were studied in order to evaluate the presence and frequency of common risk factors . PATIENTS: 55 subjects of both sexes entered the study, 21 with JS (mean age 40.2; 6 F, 15 M) and 34 affected by MA (mean age 31.3; 24 F, 10 M). METHODS: All patients underwent clinical evaluation, cerebral MR, 2D-echocardiography and blood tests including coagulation parameters. RESULTS: Hypertension, hypercholesterolemia, diabetes mellitus and smoking were more frequent in JS. Anti-phospholipid antibodies (APA) and resistance to activated protein C (APCr) together with the corresponding factor V Leiden mutation (LEI) were present in 19% of JS patients. As far sa MA patients were concerned, 19% had APCr and LEI ; 3% were deficient in protein C and 12% in protein S. DISCUSSION: APCr resistance due to LEI appears as the only common risk factor in JS and MA, showing a similar frequency in both conditions (19%) which is higher than in the general population (2-6%).
| Original language | English |
|---|---|
| Pages (from-to) | 46 |
| Number of pages | 1 |
| Journal | Italian Journal of Neurological Sciences |
| Volume | 18 |
| Issue number | 4 |
| Publication status | Published - 1997 |
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ASJC Scopus subject areas
- Neuroscience(all)
- Clinical Neurology
Cite this
Juvenile stroke and migraine with aura : Evaluation of common risk factors. / Moschiano, F.; D'Amico, D.; Leone, M.; Ariano, C.; Ciusani, E.; Elba, N.; Schieroni, F.; Bussone, G.
In: Italian Journal of Neurological Sciences, Vol. 18, No. 4, 1997, p. 46.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Juvenile stroke and migraine with aura
T2 - Evaluation of common risk factors
AU - Moschiano, F.
AU - D'Amico, D.
AU - Leone, M.
AU - Ariano, C.
AU - Ciusani, E.
AU - Elba, N.
AU - Schieroni, F.
AU - Bussone, G.
PY - 1997
Y1 - 1997
N2 - ABVI: Two groups of young adults with juvenile stroke (JS) or migraine with aura (MA) were studied in order to evaluate the presence and frequency of common risk factors . PATIENTS: 55 subjects of both sexes entered the study, 21 with JS (mean age 40.2; 6 F, 15 M) and 34 affected by MA (mean age 31.3; 24 F, 10 M). METHODS: All patients underwent clinical evaluation, cerebral MR, 2D-echocardiography and blood tests including coagulation parameters. RESULTS: Hypertension, hypercholesterolemia, diabetes mellitus and smoking were more frequent in JS. Anti-phospholipid antibodies (APA) and resistance to activated protein C (APCr) together with the corresponding factor V Leiden mutation (LEI) were present in 19% of JS patients. As far sa MA patients were concerned, 19% had APCr and LEI ; 3% were deficient in protein C and 12% in protein S. DISCUSSION: APCr resistance due to LEI appears as the only common risk factor in JS and MA, showing a similar frequency in both conditions (19%) which is higher than in the general population (2-6%).
AB - ABVI: Two groups of young adults with juvenile stroke (JS) or migraine with aura (MA) were studied in order to evaluate the presence and frequency of common risk factors . PATIENTS: 55 subjects of both sexes entered the study, 21 with JS (mean age 40.2; 6 F, 15 M) and 34 affected by MA (mean age 31.3; 24 F, 10 M). METHODS: All patients underwent clinical evaluation, cerebral MR, 2D-echocardiography and blood tests including coagulation parameters. RESULTS: Hypertension, hypercholesterolemia, diabetes mellitus and smoking were more frequent in JS. Anti-phospholipid antibodies (APA) and resistance to activated protein C (APCr) together with the corresponding factor V Leiden mutation (LEI) were present in 19% of JS patients. As far sa MA patients were concerned, 19% had APCr and LEI ; 3% were deficient in protein C and 12% in protein S. DISCUSSION: APCr resistance due to LEI appears as the only common risk factor in JS and MA, showing a similar frequency in both conditions (19%) which is higher than in the general population (2-6%).
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UR - http://www.scopus.com/inward/citedby.url?scp=33746343375&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:33746343375
VL - 18
SP - 46
JO - Italian Journal of Neurological Sciences
JF - Italian Journal of Neurological Sciences
SN - 0392-0461
IS - 4
ER -