Kaposi's sarcoma and AIDS: Frequency of gastrointestinal involvement and its effect on survival: A prospective study in a heterogeneous population

F. Parente, M. Cernuschi, G. Orlando, G. Rizzardini, A. Lazzarin, G. Bianchi Porro

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The frequency and distribution of gastrointestinal Kaposi's sarcoma were pro spectively investigated in 33 consecutive AIDS patients with heterogeneous risk factors and established skin or lymph-node disease. The influence of visceral involvement and degree of immunosuppression at the time of diagnosis on patient survival was also evaluated. Gastrointestinal lesions were found in 17 cases (51 %: 5 patients (15 % had both upper and lower GI tract involvement, 8 patients (24 % had only gastroduodenal lesions, and 4 (12 % only lower tract disease. No difference in the frequency of visceral involvement was found between the two major risk groups (homosexuals and intravenous drug abusers). The degree of immunosuppression at diagnosis was the major determinant of survival, whereas gastrointestinal involvement did not in itself significantly influence patient survival. Morbidity from enteric Kaposi's sarcoma was quite low, 80 % of these lesions being clinically silent during the follow-up period.

Original languageEnglish
Pages (from-to)1007-1012
Number of pages6
JournalScandinavian Journal of Gastroenterology
Volume26
Issue number10
DOIs
Publication statusPublished - 1991

Fingerprint

Kaposi's Sarcoma
Acquired Immunodeficiency Syndrome
Prospective Studies
Survival
Population
Immunosuppression
Lower Gastrointestinal Tract
Upper Gastrointestinal Tract
Drug Users
Lymph Nodes
Morbidity
Skin

Keywords

  • AIDS
  • Gastrointestinal involvement
  • Kaposi's sarcoma
  • Survival

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Kaposi's sarcoma and AIDS : Frequency of gastrointestinal involvement and its effect on survival: A prospective study in a heterogeneous population. / Parente, F.; Cernuschi, M.; Orlando, G.; Rizzardini, G.; Lazzarin, A.; Porro, G. Bianchi.

In: Scandinavian Journal of Gastroenterology, Vol. 26, No. 10, 1991, p. 1007-1012.

Research output: Contribution to journalArticle

Parente, F. ; Cernuschi, M. ; Orlando, G. ; Rizzardini, G. ; Lazzarin, A. ; Porro, G. Bianchi. / Kaposi's sarcoma and AIDS : Frequency of gastrointestinal involvement and its effect on survival: A prospective study in a heterogeneous population. In: Scandinavian Journal of Gastroenterology. 1991 ; Vol. 26, No. 10. pp. 1007-1012.
@article{26f0b31f7bf0441ab5383f99626b3df4,
title = "Kaposi's sarcoma and AIDS: Frequency of gastrointestinal involvement and its effect on survival: A prospective study in a heterogeneous population",
abstract = "The frequency and distribution of gastrointestinal Kaposi's sarcoma were pro spectively investigated in 33 consecutive AIDS patients with heterogeneous risk factors and established skin or lymph-node disease. The influence of visceral involvement and degree of immunosuppression at the time of diagnosis on patient survival was also evaluated. Gastrointestinal lesions were found in 17 cases (51 {\%}: 5 patients (15 {\%} had both upper and lower GI tract involvement, 8 patients (24 {\%} had only gastroduodenal lesions, and 4 (12 {\%} only lower tract disease. No difference in the frequency of visceral involvement was found between the two major risk groups (homosexuals and intravenous drug abusers). The degree of immunosuppression at diagnosis was the major determinant of survival, whereas gastrointestinal involvement did not in itself significantly influence patient survival. Morbidity from enteric Kaposi's sarcoma was quite low, 80 {\%} of these lesions being clinically silent during the follow-up period.",
keywords = "AIDS, Gastrointestinal involvement, Kaposi's sarcoma, Survival",
author = "F. Parente and M. Cernuschi and G. Orlando and G. Rizzardini and A. Lazzarin and Porro, {G. Bianchi}",
year = "1991",
doi = "10.3109/00365529109003949",
language = "English",
volume = "26",
pages = "1007--1012",
journal = "Scandinavian Journal of Gastroenterology",
issn = "0036-5521",
publisher = "Informa Healthcare",
number = "10",

}

TY - JOUR

T1 - Kaposi's sarcoma and AIDS

T2 - Frequency of gastrointestinal involvement and its effect on survival: A prospective study in a heterogeneous population

AU - Parente, F.

AU - Cernuschi, M.

AU - Orlando, G.

AU - Rizzardini, G.

AU - Lazzarin, A.

AU - Porro, G. Bianchi

PY - 1991

Y1 - 1991

N2 - The frequency and distribution of gastrointestinal Kaposi's sarcoma were pro spectively investigated in 33 consecutive AIDS patients with heterogeneous risk factors and established skin or lymph-node disease. The influence of visceral involvement and degree of immunosuppression at the time of diagnosis on patient survival was also evaluated. Gastrointestinal lesions were found in 17 cases (51 %: 5 patients (15 % had both upper and lower GI tract involvement, 8 patients (24 % had only gastroduodenal lesions, and 4 (12 % only lower tract disease. No difference in the frequency of visceral involvement was found between the two major risk groups (homosexuals and intravenous drug abusers). The degree of immunosuppression at diagnosis was the major determinant of survival, whereas gastrointestinal involvement did not in itself significantly influence patient survival. Morbidity from enteric Kaposi's sarcoma was quite low, 80 % of these lesions being clinically silent during the follow-up period.

AB - The frequency and distribution of gastrointestinal Kaposi's sarcoma were pro spectively investigated in 33 consecutive AIDS patients with heterogeneous risk factors and established skin or lymph-node disease. The influence of visceral involvement and degree of immunosuppression at the time of diagnosis on patient survival was also evaluated. Gastrointestinal lesions were found in 17 cases (51 %: 5 patients (15 % had both upper and lower GI tract involvement, 8 patients (24 % had only gastroduodenal lesions, and 4 (12 % only lower tract disease. No difference in the frequency of visceral involvement was found between the two major risk groups (homosexuals and intravenous drug abusers). The degree of immunosuppression at diagnosis was the major determinant of survival, whereas gastrointestinal involvement did not in itself significantly influence patient survival. Morbidity from enteric Kaposi's sarcoma was quite low, 80 % of these lesions being clinically silent during the follow-up period.

KW - AIDS

KW - Gastrointestinal involvement

KW - Kaposi's sarcoma

KW - Survival

UR - http://www.scopus.com/inward/record.url?scp=0025947795&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025947795&partnerID=8YFLogxK

U2 - 10.3109/00365529109003949

DO - 10.3109/00365529109003949

M3 - Article

C2 - 1947766

AN - SCOPUS:0025947795

VL - 26

SP - 1007

EP - 1012

JO - Scandinavian Journal of Gastroenterology

JF - Scandinavian Journal of Gastroenterology

SN - 0036-5521

IS - 10

ER -