Kaposi's sarcoma and AIDS: Frequency of gastrointestinal involvement and its effect on survival: A prospective study in a heterogeneous population

F. Parente, M. Cernuschi, G. Orlando, G. Rizzardini, A. Lazzarin, G. Bianchi Porro

Research output: Contribution to journalArticle

Abstract

The frequency and distribution of gastrointestinal Kaposi's sarcoma were pro spectively investigated in 33 consecutive AIDS patients with heterogeneous risk factors and established skin or lymph-node disease. The influence of visceral involvement and degree of immunosuppression at the time of diagnosis on patient survival was also evaluated. Gastrointestinal lesions were found in 17 cases (51 %: 5 patients (15 % had both upper and lower GI tract involvement, 8 patients (24 % had only gastroduodenal lesions, and 4 (12 % only lower tract disease. No difference in the frequency of visceral involvement was found between the two major risk groups (homosexuals and intravenous drug abusers). The degree of immunosuppression at diagnosis was the major determinant of survival, whereas gastrointestinal involvement did not in itself significantly influence patient survival. Morbidity from enteric Kaposi's sarcoma was quite low, 80 % of these lesions being clinically silent during the follow-up period.

Original languageEnglish
Pages (from-to)1007-1012
Number of pages6
JournalScandinavian Journal of Gastroenterology
Volume26
Issue number10
DOIs
Publication statusPublished - 1991

Keywords

  • AIDS
  • Gastrointestinal involvement
  • Kaposi's sarcoma
  • Survival

ASJC Scopus subject areas

  • Gastroenterology

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