Kawasaki disease: Guidelines of the Italian Society of Pediatrics, part i - Definition, epidemiology, etiopathogenesis, clinical expression and management of the acute phase

A. Marchesi, I. Tarissi De Jacobis, D. Rigante, A. Rimini, W. Malorni, G. Corsello, G. Bossi, S. Buonuomo, F. Cardinale, E. Cortis, F. De Benedetti, A. De Zorzi, M. Duse, D. Del Principe, R.M. Dellepiane, L. D'Isanto, M. El Hachem, S. Esposito, F. Falcini, U. GiordanoM.C. Maggio, S. Mannarino, G. Marseglia, S. Martino, G. Marucci, R. Massaro, C. Pescosolido, D. Pietraforte, M.C. Pietrogrande, P. Salice, A. Secinaro, E. Straface, A. Villani

Research output: Contribution to journalArticle

Abstract

The primary purpose of these practical guidelines related to Kawasaki disease (KD) is to contribute to prompt diagnosis and appropriate treatment on the basis of different specialists' contributions in the field. A set of 40 recommendations is provided, divided in two parts: the first describes the definition of KD, its epidemiology, etiopathogenetic hints, presentation, clinical course and general management, including treatment of the acute phase, through specific 23 recommendations. Their application is aimed at improving the rate of treatment with intravenous immunoglobulin and the overall potential development of coronary artery abnormalities in KD. Guidelines, however, should not be considered a norm that limits treatment options of pediatricians and practitioners, as treatment modalities other than those recommended may be required as a result of peculiar medical circumstances, patient's condition, and disease severity or complications. © 2018 The Author(s).
Original languageEnglish
JournalItalian Journal of Pediatrics
Volume44
Issue number1
DOIs
Publication statusPublished - 2018

Keywords

  • acetylsalicylic acid
  • immunoglobulin
  • vaccine
  • immunoglobulin, acute disease
  • acute kidney failure
  • adverse event
  • anaphylaxis
  • atherogenesis
  • blood clotting
  • cardiovascular disease
  • chill
  • chronic disease
  • clinical feature
  • differential diagnosis
  • disease course
  • dose response
  • drug efficacy
  • drug mechanism
  • dyslipidemia
  • echocardiography
  • hemolytic anemia
  • human
  • hypotension
  • innate immunity
  • jaundice
  • laboratory test
  • liver dysfunction
  • liver failure
  • lung edema
  • meningitis
  • mucocutaneous lymph node syndrome
  • pathophysiology
  • practice guideline
  • prevalence
  • recurrence risk
  • Review
  • risk factor
  • symptom
  • thrombocytopenia
  • treatment indication
  • vaccination
  • acute disease
  • disease exacerbation
  • disease management
  • female
  • Italy
  • male
  • medical society
  • meta analysis
  • pediatrics
  • prognosis
  • randomized controlled trial (topic)
  • retrospective study
  • risk assessment
  • severity of illness index
  • standards
  • treatment outcome, Acute Disease
  • Disease Management
  • Disease Progression
  • Female
  • Humans
  • Immunoglobulins, Intravenous
  • Male
  • Mucocutaneous Lymph Node Syndrome
  • Pediatrics
  • Practice Guidelines as Topic
  • Prognosis
  • Randomized Controlled Trials as Topic
  • Retrospective Studies
  • Risk Assessment
  • Severity of Illness Index
  • Societies, Medical
  • Treatment Outcome

Fingerprint Dive into the research topics of 'Kawasaki disease: Guidelines of the Italian Society of Pediatrics, part i - Definition, epidemiology, etiopathogenesis, clinical expression and management of the acute phase'. Together they form a unique fingerprint.

  • Cite this

    Marchesi, A., Tarissi De Jacobis, I., Rigante, D., Rimini, A., Malorni, W., Corsello, G., Bossi, G., Buonuomo, S., Cardinale, F., Cortis, E., De Benedetti, F., De Zorzi, A., Duse, M., Del Principe, D., Dellepiane, R. M., D'Isanto, L., El Hachem, M., Esposito, S., Falcini, F., ... Villani, A. (2018). Kawasaki disease: Guidelines of the Italian Society of Pediatrics, part i - Definition, epidemiology, etiopathogenesis, clinical expression and management of the acute phase. Italian Journal of Pediatrics, 44(1). https://doi.org/10.1186/s13052-018-0536-3