Kawasaki syndrome and concurrent Coxsackie virus B3 infection

Donato Rigante, Luca Cantarini, Marco Piastra, Donatella Francesca Angelone, Piero Valentini, Manuela Pardeo, Danilo Buonsenso, Angelica Bibiana Delogu, Daniele Serranti, Alessia De Nisco, Adele Compagnone, Gabriella De Rosa

Research output: Contribution to journalArticle

Abstract

We describe two previously healthy children who were hospitalized in the same period in different departments of our University with clinical signs of Kawasaki syndrome, which were treated with intravenous immunoglobulins and acetylsalicylic acid: in both cases, Coxsackie virus infection was concurrently demonstrated by enzyme-linked immunosorbent assay, and complement fixation test identified antibodies to serotype B3. In the acute phase, both patients presented hyperechogenic coronary arteries, but no cardiologic sequels in the mid term. The etiological relationship between Kawasaki syndrome and Coxsackie viruses is only hypothetical; however, the eventual identification of ad hoc environmental triggers is advisable in front of children with Kawasaki syndrome, with the aim of optimizing epidemiological surveillance and understanding the intimate biological events of this condition.

Original languageEnglish
Pages (from-to)4037-4040
Number of pages4
JournalRheumatology International
Volume32
Issue number12
DOIs
Publication statusPublished - Dec 2012

Fingerprint

Coxsackievirus Infections
Mucocutaneous Lymph Node Syndrome
Complement Fixation Tests
Enterovirus
Intravenous Immunoglobulins
Aspirin
Coronary Vessels
Enzyme-Linked Immunosorbent Assay
Antibodies

Keywords

  • Coxsackie virus type B3
  • Kawasaki syndrome

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy

Cite this

Rigante, D., Cantarini, L., Piastra, M., Angelone, D. F., Valentini, P., Pardeo, M., ... De Rosa, G. (2012). Kawasaki syndrome and concurrent Coxsackie virus B3 infection. Rheumatology International, 32(12), 4037-4040. https://doi.org/10.1007/s00296-010-1613-0

Kawasaki syndrome and concurrent Coxsackie virus B3 infection. / Rigante, Donato; Cantarini, Luca; Piastra, Marco; Angelone, Donatella Francesca; Valentini, Piero; Pardeo, Manuela; Buonsenso, Danilo; Delogu, Angelica Bibiana; Serranti, Daniele; De Nisco, Alessia; Compagnone, Adele; De Rosa, Gabriella.

In: Rheumatology International, Vol. 32, No. 12, 12.2012, p. 4037-4040.

Research output: Contribution to journalArticle

Rigante, D, Cantarini, L, Piastra, M, Angelone, DF, Valentini, P, Pardeo, M, Buonsenso, D, Delogu, AB, Serranti, D, De Nisco, A, Compagnone, A & De Rosa, G 2012, 'Kawasaki syndrome and concurrent Coxsackie virus B3 infection', Rheumatology International, vol. 32, no. 12, pp. 4037-4040. https://doi.org/10.1007/s00296-010-1613-0
Rigante D, Cantarini L, Piastra M, Angelone DF, Valentini P, Pardeo M et al. Kawasaki syndrome and concurrent Coxsackie virus B3 infection. Rheumatology International. 2012 Dec;32(12):4037-4040. https://doi.org/10.1007/s00296-010-1613-0
Rigante, Donato ; Cantarini, Luca ; Piastra, Marco ; Angelone, Donatella Francesca ; Valentini, Piero ; Pardeo, Manuela ; Buonsenso, Danilo ; Delogu, Angelica Bibiana ; Serranti, Daniele ; De Nisco, Alessia ; Compagnone, Adele ; De Rosa, Gabriella. / Kawasaki syndrome and concurrent Coxsackie virus B3 infection. In: Rheumatology International. 2012 ; Vol. 32, No. 12. pp. 4037-4040.
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