Il ketoprofene sale di lisina nelle otiti medie in eta pediatrica

Translated title of the contribution: Ketoprofen lysine salt in pediatric otitis media in childhood. A controlled study versus niflumic acid

V. Tarantino, R. D'Agostino, A. Melagrana, A. Porcu

Research output: Contribution to journalArticle

Abstract

Aim. Ketoprofen lysine salt (KSL), in a suppositary formula, was experimented in a controlled study versus niflumic acid in the treatment of pediatric acute otitis media (AOM). Methods. After randomisation, forty patients with AOM were treated for 8 days in two groups: half received 3 suppositaries of KSL a day and half niflumic acid in an analogous formulation using the same dosage. Differences in efficacy included: otoscopic evaluation, audiological evaluation, pain and fever. Results. Both drugs showed a marked antalgic and antipiretic action leading to a clear reduction of symptoms. This effect was significantly more rapid and intense in the KSL- treated group. Systemic tolerability was good using both drugs: collateral effects and/or alterations of blood chemical parameters were not observed in any patients. Conclusions. The use of KSL was found to be efficacious and well tolerated, thus representing a valid choice for the treatment of pediatric AOM in comparison to other NSAIDS.

Translated title of the contributionKetoprofen lysine salt in pediatric otitis media in childhood. A controlled study versus niflumic acid
Original languageItalian
Pages (from-to)205-209
Number of pages5
JournalOtorinolaringologia
Volume47
Issue number4
Publication statusPublished - 1997

ASJC Scopus subject areas

  • Otorhinolaryngology

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    Tarantino, V., D'Agostino, R., Melagrana, A., & Porcu, A. (1997). Il ketoprofene sale di lisina nelle otiti medie in eta pediatrica. Otorinolaringologia, 47(4), 205-209.