Ki-67 antigen expression in lymphocytes of cattle infected with bovine leukemia virus (BLV).

G. Gentile, M. Cipone, C. Tassi, S. Pileri, P. Tazzari

Research output: Contribution to journalArticlepeer-review

Abstract

The Ki-67 monoclonal antibody, which recognizes an antigen present on the nuclear membrane surface of mammalian cells in the replication phase, has been used for the determination of the cellular cycle of peripheral blood lymphocytes on a group of cattle positive for bovine leukemia virus (BLV) and with blood values showing a persistent lymphocytosis. The results obtained have shown that: 1. Both of the techniques used (immunofluorescence and immunoperoxidase) are easily applicable and give uniform results; 2. Cattle with a persistent lymphocytosis show an absolute number of cells in cycle significantly more elevated compared with cattle positive for BLV with normal blood values.

Original languageEnglish
Pages (from-to)206-208
Number of pages3
JournalDeutsche Tierarztliche Wochenschrift
Volume99
Issue number5
Publication statusPublished - May 1992

ASJC Scopus subject areas

  • veterinary(all)

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