Kidney Transplantation Combined With Other Organs in Bologna

An Update

R. Bertelli, B. Nardo, G. Cavallari, G. Ercolani, A. Lauro, F. Neri, M. Tsivian, G. L. Grazi, P. M. Mikus, E. Pilato, E. Mikus, G. Arpesella, A. D. Pinna, S. Stefoni, G. Fuga, A. Faenza

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: We retrospectively reviewed our experience in combined liver-kidney (L-KT) and heart-kidney (H-KT) transplantations. Patients and Methods: Between January 1997 and April 2007, we performed 25 L-KT and 5 H-KT. Patient mean age was 51 ± 8 years in L-KT and 43 ± 11 years in H-KT. The main cause of liver failure was chronic viral hepatitis (14 cases). Etiology of heart failure was dilated cardiomyopathy and hypertrophic cardiomyopathy (4 and 1 patients, respectively). The main causes of renal failure in L-KT were chronic glomerulonephritis (n = 8) and polycystic disease (n = 7). Etiology of renal failure in H-KT was interstitial nephropathy (n = 2), vascular nephropathy (n = 2), and chronic glomerulonephritis (n = 1). Results: Mean follow-up was 32 ± 26 months in L-KT and 24 ± 17 months in H-KT. Immunosuppression was cyclosporine-based (n = 4) or tacrolimus-based (n = 21) in L-KT and cyclosporine-based in H-KT. Acute rejection rate was 8% for both liver and kidney in L-KT; 80% (mild) for heart and 40% for kidney in H-KT. In the L-KT group, there was no primary graft nonfunction (PGNF). Two patients experienced liver delayed graft function (DGF); 1 patient required postoperative dialysis. One-year graft and patient survivals were both 84% and overall graft and patient survival was 76%. In the H-KT group, 3 patients needed postoperative dialysis and 1 required a cardiac assistance device for 48 hours; overall graft and patient survival was 100% with good cardiac and renal functions. Conclusion: Our experience confirmed that H-KT and L-KT are safe procedures, offering good long-term results.

Original languageEnglish
Pages (from-to)1867-1868
Number of pages2
JournalTransplantation Proceedings
Volume40
Issue number6
DOIs
Publication statusPublished - Jul 2008

Fingerprint

Kidney Transplantation
Kidney
Graft Survival
Glomerulonephritis
Cyclosporine
Renal Insufficiency
Dialysis
Liver
Delayed Graft Function
Hypertrophic Cardiomyopathy
Liver Failure
Dilated Cardiomyopathy
Tacrolimus
Chronic Hepatitis
Immunosuppression
Blood Vessels
Heart Failure
Transplantation
Transplants
Equipment and Supplies

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Bertelli, R., Nardo, B., Cavallari, G., Ercolani, G., Lauro, A., Neri, F., ... Faenza, A. (2008). Kidney Transplantation Combined With Other Organs in Bologna: An Update. Transplantation Proceedings, 40(6), 1867-1868. https://doi.org/10.1016/j.transproceed.2008.05.024

Kidney Transplantation Combined With Other Organs in Bologna : An Update. / Bertelli, R.; Nardo, B.; Cavallari, G.; Ercolani, G.; Lauro, A.; Neri, F.; Tsivian, M.; Grazi, G. L.; Mikus, P. M.; Pilato, E.; Mikus, E.; Arpesella, G.; Pinna, A. D.; Stefoni, S.; Fuga, G.; Faenza, A.

In: Transplantation Proceedings, Vol. 40, No. 6, 07.2008, p. 1867-1868.

Research output: Contribution to journalArticle

Bertelli, R, Nardo, B, Cavallari, G, Ercolani, G, Lauro, A, Neri, F, Tsivian, M, Grazi, GL, Mikus, PM, Pilato, E, Mikus, E, Arpesella, G, Pinna, AD, Stefoni, S, Fuga, G & Faenza, A 2008, 'Kidney Transplantation Combined With Other Organs in Bologna: An Update', Transplantation Proceedings, vol. 40, no. 6, pp. 1867-1868. https://doi.org/10.1016/j.transproceed.2008.05.024
Bertelli R, Nardo B, Cavallari G, Ercolani G, Lauro A, Neri F et al. Kidney Transplantation Combined With Other Organs in Bologna: An Update. Transplantation Proceedings. 2008 Jul;40(6):1867-1868. https://doi.org/10.1016/j.transproceed.2008.05.024
Bertelli, R. ; Nardo, B. ; Cavallari, G. ; Ercolani, G. ; Lauro, A. ; Neri, F. ; Tsivian, M. ; Grazi, G. L. ; Mikus, P. M. ; Pilato, E. ; Mikus, E. ; Arpesella, G. ; Pinna, A. D. ; Stefoni, S. ; Fuga, G. ; Faenza, A. / Kidney Transplantation Combined With Other Organs in Bologna : An Update. In: Transplantation Proceedings. 2008 ; Vol. 40, No. 6. pp. 1867-1868.
@article{719ac05ac7804698b6932d148f0391e9,
title = "Kidney Transplantation Combined With Other Organs in Bologna: An Update",
abstract = "Background: We retrospectively reviewed our experience in combined liver-kidney (L-KT) and heart-kidney (H-KT) transplantations. Patients and Methods: Between January 1997 and April 2007, we performed 25 L-KT and 5 H-KT. Patient mean age was 51 ± 8 years in L-KT and 43 ± 11 years in H-KT. The main cause of liver failure was chronic viral hepatitis (14 cases). Etiology of heart failure was dilated cardiomyopathy and hypertrophic cardiomyopathy (4 and 1 patients, respectively). The main causes of renal failure in L-KT were chronic glomerulonephritis (n = 8) and polycystic disease (n = 7). Etiology of renal failure in H-KT was interstitial nephropathy (n = 2), vascular nephropathy (n = 2), and chronic glomerulonephritis (n = 1). Results: Mean follow-up was 32 ± 26 months in L-KT and 24 ± 17 months in H-KT. Immunosuppression was cyclosporine-based (n = 4) or tacrolimus-based (n = 21) in L-KT and cyclosporine-based in H-KT. Acute rejection rate was 8{\%} for both liver and kidney in L-KT; 80{\%} (mild) for heart and 40{\%} for kidney in H-KT. In the L-KT group, there was no primary graft nonfunction (PGNF). Two patients experienced liver delayed graft function (DGF); 1 patient required postoperative dialysis. One-year graft and patient survivals were both 84{\%} and overall graft and patient survival was 76{\%}. In the H-KT group, 3 patients needed postoperative dialysis and 1 required a cardiac assistance device for 48 hours; overall graft and patient survival was 100{\%} with good cardiac and renal functions. Conclusion: Our experience confirmed that H-KT and L-KT are safe procedures, offering good long-term results.",
author = "R. Bertelli and B. Nardo and G. Cavallari and G. Ercolani and A. Lauro and F. Neri and M. Tsivian and Grazi, {G. L.} and Mikus, {P. M.} and E. Pilato and E. Mikus and G. Arpesella and Pinna, {A. D.} and S. Stefoni and G. Fuga and A. Faenza",
year = "2008",
month = "7",
doi = "10.1016/j.transproceed.2008.05.024",
language = "English",
volume = "40",
pages = "1867--1868",
journal = "Transplantation Proceedings",
issn = "0041-1345",
publisher = "Elsevier USA",
number = "6",

}

TY - JOUR

T1 - Kidney Transplantation Combined With Other Organs in Bologna

T2 - An Update

AU - Bertelli, R.

AU - Nardo, B.

AU - Cavallari, G.

AU - Ercolani, G.

AU - Lauro, A.

AU - Neri, F.

AU - Tsivian, M.

AU - Grazi, G. L.

AU - Mikus, P. M.

AU - Pilato, E.

AU - Mikus, E.

AU - Arpesella, G.

AU - Pinna, A. D.

AU - Stefoni, S.

AU - Fuga, G.

AU - Faenza, A.

PY - 2008/7

Y1 - 2008/7

N2 - Background: We retrospectively reviewed our experience in combined liver-kidney (L-KT) and heart-kidney (H-KT) transplantations. Patients and Methods: Between January 1997 and April 2007, we performed 25 L-KT and 5 H-KT. Patient mean age was 51 ± 8 years in L-KT and 43 ± 11 years in H-KT. The main cause of liver failure was chronic viral hepatitis (14 cases). Etiology of heart failure was dilated cardiomyopathy and hypertrophic cardiomyopathy (4 and 1 patients, respectively). The main causes of renal failure in L-KT were chronic glomerulonephritis (n = 8) and polycystic disease (n = 7). Etiology of renal failure in H-KT was interstitial nephropathy (n = 2), vascular nephropathy (n = 2), and chronic glomerulonephritis (n = 1). Results: Mean follow-up was 32 ± 26 months in L-KT and 24 ± 17 months in H-KT. Immunosuppression was cyclosporine-based (n = 4) or tacrolimus-based (n = 21) in L-KT and cyclosporine-based in H-KT. Acute rejection rate was 8% for both liver and kidney in L-KT; 80% (mild) for heart and 40% for kidney in H-KT. In the L-KT group, there was no primary graft nonfunction (PGNF). Two patients experienced liver delayed graft function (DGF); 1 patient required postoperative dialysis. One-year graft and patient survivals were both 84% and overall graft and patient survival was 76%. In the H-KT group, 3 patients needed postoperative dialysis and 1 required a cardiac assistance device for 48 hours; overall graft and patient survival was 100% with good cardiac and renal functions. Conclusion: Our experience confirmed that H-KT and L-KT are safe procedures, offering good long-term results.

AB - Background: We retrospectively reviewed our experience in combined liver-kidney (L-KT) and heart-kidney (H-KT) transplantations. Patients and Methods: Between January 1997 and April 2007, we performed 25 L-KT and 5 H-KT. Patient mean age was 51 ± 8 years in L-KT and 43 ± 11 years in H-KT. The main cause of liver failure was chronic viral hepatitis (14 cases). Etiology of heart failure was dilated cardiomyopathy and hypertrophic cardiomyopathy (4 and 1 patients, respectively). The main causes of renal failure in L-KT were chronic glomerulonephritis (n = 8) and polycystic disease (n = 7). Etiology of renal failure in H-KT was interstitial nephropathy (n = 2), vascular nephropathy (n = 2), and chronic glomerulonephritis (n = 1). Results: Mean follow-up was 32 ± 26 months in L-KT and 24 ± 17 months in H-KT. Immunosuppression was cyclosporine-based (n = 4) or tacrolimus-based (n = 21) in L-KT and cyclosporine-based in H-KT. Acute rejection rate was 8% for both liver and kidney in L-KT; 80% (mild) for heart and 40% for kidney in H-KT. In the L-KT group, there was no primary graft nonfunction (PGNF). Two patients experienced liver delayed graft function (DGF); 1 patient required postoperative dialysis. One-year graft and patient survivals were both 84% and overall graft and patient survival was 76%. In the H-KT group, 3 patients needed postoperative dialysis and 1 required a cardiac assistance device for 48 hours; overall graft and patient survival was 100% with good cardiac and renal functions. Conclusion: Our experience confirmed that H-KT and L-KT are safe procedures, offering good long-term results.

UR - http://www.scopus.com/inward/record.url?scp=48049093317&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=48049093317&partnerID=8YFLogxK

U2 - 10.1016/j.transproceed.2008.05.024

DO - 10.1016/j.transproceed.2008.05.024

M3 - Article

VL - 40

SP - 1867

EP - 1868

JO - Transplantation Proceedings

JF - Transplantation Proceedings

SN - 0041-1345

IS - 6

ER -