Kinetics and significance of serum hepatitis C virus core antigen in patients with acute hepatitis C

Agostino Cividini, Antonella Cerino, Alba Muzzi, Milena Furione, Chiara Rebucci, Laura Segagni, Marta Gatti, Vincenzo Barnaba, Mario U. Mondelli

Research output: Contribution to journalArticle


An immunoassay detecting hepatitis C virus core antigen was evaluated for its ability to predict clinical outcome in a series of patients with acute hepatitis C. In subjects who cleared the virus, core antigen was no longer detectable within 16 weeks of onset, whereas considerable fluctuations were noted among patients progressing to chronic hepatitis, one of whom showed consistently negative values despite the intermittent presence of viral RNA.

Original languageEnglish
Pages (from-to)2144-2146
Number of pages3
JournalJournal of Clinical Microbiology
Issue number5
Publication statusPublished - May 1 2003


ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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